Progerin-Induced Impairment in Wound Healing and Proliferation in Vascular Endothelial Cells
Progerin as a mutated isoform of lamin A protein was first known to induce premature atherosclerosis progression in patients with Hutchinson-Gilford progeria syndrome (HGPS), and its role in provoking an inflammatory response in vascular cells and accelerating cell senescence has been investigated r...
Main Authors: | Yizhi Jiang, Julie Y. Ji |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-03-01
|
Series: | Frontiers in Aging |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fragi.2022.844885/full |
Similar Items
-
Progerin Inhibits the Proliferation and Migration of Melanoma Cells by Regulating the Expression of Paxillin
by: Liu W, et al.
Published: (2024-03-01) -
Vascular Smooth Muscle Cell-Specific Progerin Expression Provokes Contractile Impairment in a Mouse Model of Hutchinson-Gilford Progeria Syndrome that Is Ameliorated by Nitrite Treatment
by: Lara del Campo, et al.
Published: (2020-03-01) -
Progerin Expression Induces Inflammation, Oxidative Stress and Senescence in Human Coronary Endothelial Cells
by: Guillaume Bidault, et al.
Published: (2020-05-01) -
Nucleophagic Degradation of Progerin Ameliorates Defenestration in Liver Sinusoidal Endothelium Due to SIRT1-Mediated Deacetylation of Nuclear LC3
by: Yangqiu Bai, et al.
Published: (2022-12-01) -
ZMPSTE24 Is Associated with Elevated Inflammation and Progerin mRNA
by: Moritz Messner, et al.
Published: (2020-08-01)