Prediction of recurrent currents of tooth decay among pregnant women laboratory method evaluation of antimicrobial activity of immunity oral liquid
The aim of the study was to develop a laboratory risk assessment methodology caries recurrence during pregnancy on the contents of the antimicrobial factor in innate immunity in oral fluid. Surveyed 207 pregnant women with caries of the teeth (clinical group), 31 a pregnant woman with no dental path...
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| Format: | Article |
| Language: | Russian |
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Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2015-04-01
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| Series: | Кубанский научный медицинский вестник |
| Subjects: | |
| Online Access: | https://ksma.elpub.ru/jour/article/view/312 |
| _version_ | 1797295614886674432 |
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| author | V. A. Prohodnaja T. V. Gajvoronskaja A. S. Lomova |
| author_facet | V. A. Prohodnaja T. V. Gajvoronskaja A. S. Lomova |
| author_sort | V. A. Prohodnaja |
| collection | DOAJ |
| description | The aim of the study was to develop a laboratory risk assessment methodology caries recurrence during pregnancy on the contents of the antimicrobial factor in innate immunity in oral fluid. Surveyed 207 pregnant women with caries of the teeth (clinical group), 31 a pregnant woman with no dental pathology and 32 healthy donors without physical and dental diseases. The patients in oral fluid determined three immune peptides: lactoferrin, cathelicidin LL-37 and α-defensin. In pregnant women the development of dental caries has been accompanied by increased in 2 trimester on trimester 1 level all immune peptides in saliva with the subsequent reduction in antimicrobial peptides α-defensin1-3 and cathelicidin LL37 in oral fluid in the 3 trimester. A compensatory mechanism for constraining the increase of intensity and activity of caries, the recurrence of the disease in pregnancy is increase antibacterial protein lactoferrin in saliva. In pregnant women during the first trimester of gestation when the oral fluid levels of lactoferrin above 3,08 g/ml, lowering the content of cathelicidin is below 1,9 pg/ml, caries recurrence risk goes up. |
| first_indexed | 2024-03-07T21:50:28Z |
| format | Article |
| id | doaj.art-83687eb3b84a421a8e08f47919ceac7a |
| institution | Directory Open Access Journal |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| last_indexed | 2024-03-07T21:50:28Z |
| publishDate | 2015-04-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj.art-83687eb3b84a421a8e08f47919ceac7a2024-02-25T10:57:16ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442015-04-01213113610.25207/1608-6228-2015-2-131-136312Prediction of recurrent currents of tooth decay among pregnant women laboratory method evaluation of antimicrobial activity of immunity oral liquidV. A. Prohodnaja0T. V. Gajvoronskaja1A. S. Lomova2Rostov state medical universityKuban state medical universityRostov state medical universityThe aim of the study was to develop a laboratory risk assessment methodology caries recurrence during pregnancy on the contents of the antimicrobial factor in innate immunity in oral fluid. Surveyed 207 pregnant women with caries of the teeth (clinical group), 31 a pregnant woman with no dental pathology and 32 healthy donors without physical and dental diseases. The patients in oral fluid determined three immune peptides: lactoferrin, cathelicidin LL-37 and α-defensin. In pregnant women the development of dental caries has been accompanied by increased in 2 trimester on trimester 1 level all immune peptides in saliva with the subsequent reduction in antimicrobial peptides α-defensin1-3 and cathelicidin LL37 in oral fluid in the 3 trimester. A compensatory mechanism for constraining the increase of intensity and activity of caries, the recurrence of the disease in pregnancy is increase antibacterial protein lactoferrin in saliva. In pregnant women during the first trimester of gestation when the oral fluid levels of lactoferrin above 3,08 g/ml, lowering the content of cathelicidin is below 1,9 pg/ml, caries recurrence risk goes up.https://ksma.elpub.ru/jour/article/view/312беременностькариес зубовлактоферриндефензиныкателицидина ll-37pregnancydental carieslactoferrindefensinscathelicidin ll-37 |
| spellingShingle | V. A. Prohodnaja T. V. Gajvoronskaja A. S. Lomova Prediction of recurrent currents of tooth decay among pregnant women laboratory method evaluation of antimicrobial activity of immunity oral liquid Кубанский научный медицинский вестник беременность кариес зубов лактоферрин дефензины кателицидина ll-37 pregnancy dental caries lactoferrin defensins cathelicidin ll-37 |
| title | Prediction of recurrent currents of tooth decay among pregnant women laboratory method evaluation of antimicrobial activity of immunity oral liquid |
| title_full | Prediction of recurrent currents of tooth decay among pregnant women laboratory method evaluation of antimicrobial activity of immunity oral liquid |
| title_fullStr | Prediction of recurrent currents of tooth decay among pregnant women laboratory method evaluation of antimicrobial activity of immunity oral liquid |
| title_full_unstemmed | Prediction of recurrent currents of tooth decay among pregnant women laboratory method evaluation of antimicrobial activity of immunity oral liquid |
| title_short | Prediction of recurrent currents of tooth decay among pregnant women laboratory method evaluation of antimicrobial activity of immunity oral liquid |
| title_sort | prediction of recurrent currents of tooth decay among pregnant women laboratory method evaluation of antimicrobial activity of immunity oral liquid |
| topic | беременность кариес зубов лактоферрин дефензины кателицидина ll-37 pregnancy dental caries lactoferrin defensins cathelicidin ll-37 |
| url | https://ksma.elpub.ru/jour/article/view/312 |
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