Higher weight-adjusted waist index is associated with increased likelihood of kidney stones
ObjectivesThe objective of this study was to evaluate the association between weight-adjusted waist index (WWI) and the prevalence of kidney stones among adults in the United States.MethodsThe cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) span...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1234440/full |
| _version_ | 1797679237755305984 |
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| author | Hangyu Liu Yang Ma Lungang Shi |
| author_facet | Hangyu Liu Yang Ma Lungang Shi |
| author_sort | Hangyu Liu |
| collection | DOAJ |
| description | ObjectivesThe objective of this study was to evaluate the association between weight-adjusted waist index (WWI) and the prevalence of kidney stones among adults in the United States.MethodsThe cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) spanning the years 2007-2018. A total of 31,344 participants were categorized into two groups: those with kidney stones and those without. WWI was determined by dividing waist circumference (cm) by the square root of body weight (kg). To examine the relationship between kidney stones and WWI, multivariate logistic regression models, smoothed curve fitting, and weighted generalized additive model (GAM) regression were employed. Subgroup analysis and interaction tests were conducted to explore the stability of this association across different groups.ResultsThe final analysis comprised a total of 31,344 participants, including 2,928 individuals who had a history of kidney stones. In the fully adjusted model, an increase in WWI exhibited a positive correlation with the prevalence of kidney stones (OR=1.34, 95% CI: 1.18-1.51). When WWI was converted into quartiles (Q1-Q4), participants in the highest quartile (Q4) had a 69% greater risk of developing kidney stones compared to those in the lowest quartile (Q1) (OR=1.69, 95% CI: 1.28-2.25). This positive association was particularly notable among non-diabetic patients.ConclusionOur study demonstrates a significant positive association between weight-adjusted waist index levels and an elevated prevalence of kidney stones among US adults. Furthermore, this research highlights the potential utility of weight-adjusted waist index in the prevention of kidney stones in the overall population. This relationship is limited and further research is needed to test this hypothesis. |
| first_indexed | 2024-03-11T23:11:36Z |
| format | Article |
| id | doaj.art-836960f3abd54a9bb8679604dd44f8bb |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-11T23:11:36Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-836960f3abd54a9bb8679604dd44f8bb2023-09-21T08:33:23ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-09-011410.3389/fendo.2023.12344401234440Higher weight-adjusted waist index is associated with increased likelihood of kidney stonesHangyu Liu0Yang Ma1Lungang Shi2Department of Plastic Surgery and Burn Center, the Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, ChinaDepartment of Plastic Surgery, Meizhou Clinical Institute of Shantou University Medical College, Meizhou, Guangdong, ChinaDepartment of Plastic Surgery, Meizhou Clinical Institute of Shantou University Medical College, Meizhou, Guangdong, ChinaObjectivesThe objective of this study was to evaluate the association between weight-adjusted waist index (WWI) and the prevalence of kidney stones among adults in the United States.MethodsThe cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) spanning the years 2007-2018. A total of 31,344 participants were categorized into two groups: those with kidney stones and those without. WWI was determined by dividing waist circumference (cm) by the square root of body weight (kg). To examine the relationship between kidney stones and WWI, multivariate logistic regression models, smoothed curve fitting, and weighted generalized additive model (GAM) regression were employed. Subgroup analysis and interaction tests were conducted to explore the stability of this association across different groups.ResultsThe final analysis comprised a total of 31,344 participants, including 2,928 individuals who had a history of kidney stones. In the fully adjusted model, an increase in WWI exhibited a positive correlation with the prevalence of kidney stones (OR=1.34, 95% CI: 1.18-1.51). When WWI was converted into quartiles (Q1-Q4), participants in the highest quartile (Q4) had a 69% greater risk of developing kidney stones compared to those in the lowest quartile (Q1) (OR=1.69, 95% CI: 1.28-2.25). This positive association was particularly notable among non-diabetic patients.ConclusionOur study demonstrates a significant positive association between weight-adjusted waist index levels and an elevated prevalence of kidney stones among US adults. Furthermore, this research highlights the potential utility of weight-adjusted waist index in the prevention of kidney stones in the overall population. This relationship is limited and further research is needed to test this hypothesis.https://www.frontiersin.org/articles/10.3389/fendo.2023.1234440/fullweight-adjusted waist indexkidney stoneNHANESobesecross-sectional study |
| spellingShingle | Hangyu Liu Yang Ma Lungang Shi Higher weight-adjusted waist index is associated with increased likelihood of kidney stones Frontiers in Endocrinology weight-adjusted waist index kidney stone NHANES obese cross-sectional study |
| title | Higher weight-adjusted waist index is associated with increased likelihood of kidney stones |
| title_full | Higher weight-adjusted waist index is associated with increased likelihood of kidney stones |
| title_fullStr | Higher weight-adjusted waist index is associated with increased likelihood of kidney stones |
| title_full_unstemmed | Higher weight-adjusted waist index is associated with increased likelihood of kidney stones |
| title_short | Higher weight-adjusted waist index is associated with increased likelihood of kidney stones |
| title_sort | higher weight adjusted waist index is associated with increased likelihood of kidney stones |
| topic | weight-adjusted waist index kidney stone NHANES obese cross-sectional study |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1234440/full |
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