Unraveling the Behavior of Intrinsically Disordered Protein c‑Myc: A Study Utilizing Gaussian-Accelerated Molecular Dynamics

Unraveling the Behavior of Intrinsically Disordered Protein c‑Myc: A Study Utilizing Gaussian-Accelerated Molecular Dynamics

Bibliographic Details
Main Authors:	Kavinda Kashi Juliyan Gunasinghe, Taufiq Rahman, Xavier Chee Wezen
Format:	Article
Language:	English
Published:	American Chemical Society 2023-12-01
Series:	ACS Omega
Online Access:	https://doi.org/10.1021/acsomega.3c05822

Similar Items

In Silico Modeling and Characterization of Epstein–Barr Virus Latent Membrane Protein 1 Protein
by: Dayang-Sharyati D. A. Salam, et al.
Published: (2024-12-01)

Structural and Biophysical Insights into the Function of the Intrinsically Disordered Myc Oncoprotein
by: Marie-Eve Beaulieu, et al.
Published: (2020-04-01)

Unraveling MYC’s Role in Orchestrating Tumor Intrinsic and Tumor Microenvironment Interactions Driving Tumorigenesis and Drug Resistance
by: Zinab O. Doha, et al.
Published: (2023-09-01)

Optimization of Molecular Dynamics Simulations of c-MYC<sup>1-88</sup>—An Intrinsically Disordered System
by: Sandra S. Sullivan, et al.
Published: (2020-07-01)

Human soluble CD39 displays substrate inhibition in a substrate-specific manner
by: Venkat M. K. Vadlamani, et al.
Published: (2023-06-01)

High Intrinsic Oncogenic Potential in the Myc-Box-Deficient <i>Hydra</i> Myc3 Protein
by: Marion Lechable, et al.
Published: (2023-04-01)

Intrinsically Interpretable Gaussian Mixture Model
by: Nourah Alangari, et al.
Published: (2023-03-01)

Gaussian accelerated molecular dynamics simulations facilitate prediction of the permeability of cyclic peptides
by: Nicolas Frazee, et al.
Published: (2024-01-01)

Unraveling the mechanisms of intrinsic drug resistance in Mycobacterium tuberculosis
by: Nicholas C. Poulton, et al.
Published: (2022-10-01)

Intrinsic rotation driven by turbulent acceleration
by: Barnes, M, et al.
Published: (2018)

Continuous quantum measurement for general Gaussian unravelings can exist
by: Nina Megier, et al.
Published: (2020-12-01)

Molecular genetics of timing in intrinsic circadian rhythm sleep disorders.
by: Wijnen, H, et al.
Published: (2002)

Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway.
by: Meenu R Pillai, et al.
Published: (2019-01-01)

Off-axis elliptic Gaussian beams with an intrinsic orbital angular momentum
by: A.A. Kovalev, et al.
Published: (2021-12-01)

Molecular investigation of antimicrobial peptides against Helicobacter pylori proteins using a peptide-protein docking approach
by: Alfizah Hanafiah, et al.
Published: (2024-03-01)

Impacts of Mutations in the P-Loop on Conformational Alterations of KRAS Investigated with Gaussian Accelerated Molecular Dynamics Simulations
by: Shuhua Shi, et al.
Published: (2023-03-01)

Unraveling the genomic underpinnings of unbalanced MYC break-apart FISH results using whole genome sequencing analysis
by: Marie-France Gagnon, et al.
Published: (2023-12-01)

Diffusion Acceleration with Gaussian process Estimated Reconstruction (DAGER)
by: Wu, W, et al.
Published: (2019)

The Near Constant Acceleration Gaussian Process Kernel for Tracking
by: Reece, S, et al.
Published: (2010)

Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma
by: Jimmy Lee, et al.
Published: (2018-08-01)

Molecular dynamics simulations of intrinsically disordered protein-induced membrane curvature generation
by: Wang, Yi
Published: (2025)

Altered local intrinsic neural activity and molecular architecture in internet use disorders
by: Longyao Ma, et al.
Published: (2024-10-01)

AlphaFold2 modeling and molecular dynamics simulations of an intrinsically disordered protein.
by: Hao-Bo Guo, et al.
Published: (2024-01-01)

AlphaFold2 modeling and molecular dynamics simulations of an intrinsically disordered protein
by: Hao-Bo Guo, et al.
Published: (2024-01-01)

Energy-Efficient Real-Time Hardware Acceleration for Gaussian Fitting
by: Wojtyna, Adrianna D.
Published: (2024)

Unraveling organocuprate complexity : fundamental insights into intrinsic group transfer selectivity in alkylation reactions
by: Rijs, Nicole J., et al.
Published: (2014)

Unraveling the influences of hemodynamic lag and intrinsic cerebrovascular reactivity on functional metrics in ischemic stroke
by: Luoyu Wang, et al.
Published: (2024-12-01)

Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability
by: Zhongze Wang, et al.
Published: (2023-12-01)

Probing mutation-induced conformational transformation of the GTP/M-RAS complex through Gaussian accelerated molecular dynamics simulations
by: Huayin Bao, et al.
Published: (2023-12-01)

Gaussian Accelerated Molecular Dynamics Simulations Investigation on the Mechanism of Angiotensin-Converting Enzyme (ACE) C-Domain Inhibition by Dipeptides
by: Congcong Li, et al.
Published: (2022-01-01)

Tuning the MYC response
by: Ying Zheng, et al.
Published: (2016-07-01)

Unravelling giant molecular clouds
by: Liang, F
Published: (2024)

Gaussian basis sets for molecular calculations /
by: Huzinaga, S.
Published: (1984)

Constructing ensembles for intrinsically disordered proteins
by: Stultz, Collin M., et al.
Published: (2015)

Intrinsic disorder in the human spliceosomal proteome.
by: Iga Korneta, et al.
Published: (2012-01-01)

Evolution of Intrinsic Disorder in Protein Loops
by: Fizza Mughal, et al.
Published: (2023-10-01)

The intrinsically disorderly story of Ki-67
by: Lucy Remnant, et al.
Published: (2021-08-01)

Characterizing Satellite Geometry via Accelerated 3D Gaussian Splatting
by: Van Minh Nguyen, et al.
Published: (2024-02-01)

Proton acceleration in underdense plasma by ultraintense Laguerre–Gaussian laser pulse
by: Xiaomei Zhang, et al.
Published: (2014-01-01)

MYC overexpression leads to increased chromatin interactions at superenhancers and MYC binding sites
by: See, Yi Xiang, et al.
Published: (2022)