Impact of vaccination on the incidence of varicella hospitalizations in a state in Southeast Brazil
Abstract INTRODUCTION: This study aimed to analyze cases of complicated varicella and the impact of varicella vaccination in Minas Gerais, Brazil. METHODS: This was a time series study of a territorial basis using data on varicella cases from 2010 to 2016, which was provided by the State Health...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2019-12-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100345&tlng=en |
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| author | Aline Ciabotti Dias Leiner Resende Rodrigues Altacílio Aparecido Nunes Sybelle de Souza Castro |
| author_facet | Aline Ciabotti Dias Leiner Resende Rodrigues Altacílio Aparecido Nunes Sybelle de Souza Castro |
| author_sort | Aline Ciabotti Dias |
| collection | DOAJ |
| description | Abstract INTRODUCTION: This study aimed to analyze cases of complicated varicella and the impact of varicella vaccination in Minas Gerais, Brazil. METHODS: This was a time series study of a territorial basis using data on varicella cases from 2010 to 2016, which was provided by the State Health Department of Minas Gerais on . Descriptive statistics were used for the analysis, and the generalized linear regression model proposed by Prais-Winsten was used for the time tendency, adopting a significance level of 5% and the integrated autoregressive modeling of moving averages. RESULTS: There were 1,635 cases of varicella; out of which cellulitis (44%) was the predominant complication. The home-acquired cases were 38.9% and 464 cases (40.6%) were not previously vaccinated. There was a significant decrease in the incidence coefficient when comparing the pre- and post- immunization periods, from 1.95 cases/100,000 inhabitants in 2010 to 0.24 cases/100.000 inhabitants in 2016 (p<0.05). There was a higher incidence of cases recorded among males, with higher prevalence in the age group of 1-4 years (54.7%). Lethality was higher between 5-9 years of age (44%). Mortality was higher in the age group of 0-4 years and among females (2.58/100,000 inhabitants/year). The overall trend of the incidence coefficient was a decreasing one, with an annual percentage variation. CONCLUSIONS: The number of complicated varicella cases notified decreased, coincidentally, in the post-immunization period. However, the immunization coverage period was restricted for the assessment of the correlation between immunization coverage and incidence. |
| first_indexed | 2024-04-12T14:40:01Z |
| format | Article |
| id | doaj.art-836cc5b82f8d43cb85893ebbb6c9c51a |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T14:40:01Z |
| publishDate | 2019-12-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-836cc5b82f8d43cb85893ebbb6c9c51a2022-12-22T03:28:54ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492019-12-015210.1590/0037-8682-0149-2019Impact of vaccination on the incidence of varicella hospitalizations in a state in Southeast BrazilAline Ciabotti Diashttps://orcid.org/0000-0002-4883-4130Leiner Resende RodriguesAltacílio Aparecido NunesSybelle de Souza CastroAbstract INTRODUCTION: This study aimed to analyze cases of complicated varicella and the impact of varicella vaccination in Minas Gerais, Brazil. METHODS: This was a time series study of a territorial basis using data on varicella cases from 2010 to 2016, which was provided by the State Health Department of Minas Gerais on . Descriptive statistics were used for the analysis, and the generalized linear regression model proposed by Prais-Winsten was used for the time tendency, adopting a significance level of 5% and the integrated autoregressive modeling of moving averages. RESULTS: There were 1,635 cases of varicella; out of which cellulitis (44%) was the predominant complication. The home-acquired cases were 38.9% and 464 cases (40.6%) were not previously vaccinated. There was a significant decrease in the incidence coefficient when comparing the pre- and post- immunization periods, from 1.95 cases/100,000 inhabitants in 2010 to 0.24 cases/100.000 inhabitants in 2016 (p<0.05). There was a higher incidence of cases recorded among males, with higher prevalence in the age group of 1-4 years (54.7%). Lethality was higher between 5-9 years of age (44%). Mortality was higher in the age group of 0-4 years and among females (2.58/100,000 inhabitants/year). The overall trend of the incidence coefficient was a decreasing one, with an annual percentage variation. CONCLUSIONS: The number of complicated varicella cases notified decreased, coincidentally, in the post-immunization period. However, the immunization coverage period was restricted for the assessment of the correlation between immunization coverage and incidence.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100345&tlng=enVaricellaHospitalizationImmunizationHealth programs and plansVaccination |
| spellingShingle | Aline Ciabotti Dias Leiner Resende Rodrigues Altacílio Aparecido Nunes Sybelle de Souza Castro Impact of vaccination on the incidence of varicella hospitalizations in a state in Southeast Brazil Revista da Sociedade Brasileira de Medicina Tropical Varicella Hospitalization Immunization Health programs and plans Vaccination |
| title | Impact of vaccination on the incidence of varicella hospitalizations in a state in Southeast Brazil |
| title_full | Impact of vaccination on the incidence of varicella hospitalizations in a state in Southeast Brazil |
| title_fullStr | Impact of vaccination on the incidence of varicella hospitalizations in a state in Southeast Brazil |
| title_full_unstemmed | Impact of vaccination on the incidence of varicella hospitalizations in a state in Southeast Brazil |
| title_short | Impact of vaccination on the incidence of varicella hospitalizations in a state in Southeast Brazil |
| title_sort | impact of vaccination on the incidence of varicella hospitalizations in a state in southeast brazil |
| topic | Varicella Hospitalization Immunization Health programs and plans Vaccination |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100345&tlng=en |
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