Zyflamend induces apoptosis in pancreatic cancer cells via modulation of the JNK pathway

Zyflamend induces apoptosis in pancreatic cancer cells via modulation of the JNK pathway

Abstract Background Current pharmacological therapies and treatments targeting pancreatic neuroendocrine tumors (PNETs) have proven ineffective, far too often. Therefore, there is an urgent need for alternative therapeutic approaches. Zyflamend, a combination of anti-inflammatory herbal extracts, th...

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Bibliographic Details
Main Authors: Dexter L. Puckett, Mohammed Alquraishi, Dina Alani, Samah Chahed, Dallas Donohoe, Brynn Voy, Jay Whelan, Ahmed Bettaieb
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Cell Communication and Signaling
Subjects:
Pancreatic neuroendocrine tumor cells
Zyflamend
JNK
Apoptosis
Autophagy
ER stress
Online Access:http://link.springer.com/article/10.1186/s12964-020-00609-7

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