Underestimation of airway luminal eosinophilia by quantitative sputum cytometry
Abstract Rationale On Wright-stained sputum cytospins, eosinophil differential of ≥ 1.2% is considered abnormal, and ≥ 2.3% identifies an eosinophilic endotype. We hypothesized that failure to consider free eosinophil granules (FEG), and the re-emergence (unmasking) of eosinophilia due to various re...
Main Authors: | Melanie Kjarsgaard, Adil Adatia, Anurag Bhalla, Nicola LaVigne, Katherine Radford, Chynna Huang, Manali Mukherjee, Parameswaran Nair |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-07-01
|
Series: | Allergy, Asthma & Clinical Immunology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13223-021-00567-w |
Similar Items
-
Identification of COPD Inflammatory Endotypes Using Repeated Sputum Eosinophil Counts
by: Augusta Beech, et al.
Published: (2022-10-01) -
Significance of assessment of sputum eosinophilia in bronchial asthma
by: Reshma.M1 , Sharadrutha.A2 , C.N.Prasad3
Published: (2018-04-01) -
Iron in airway macrophages and infective exacerbations of chronic obstructive pulmonary disease
by: Terence Ho, et al.
Published: (2022-01-01) -
Sputum cell counts to manage prednisone-dependent asthma: effects on FEV1 and eosinophilic exacerbations
by: Afia Aziz-Ur-Rehman, et al.
Published: (2017-04-01) -
Correlation between fractional exhaled nitric oxide and sputum eosinophilia in exacerbations of COPD
by: Gao J, et al.
Published: (2017-04-01)