Determinants of quality of life improvements in anxiety and depressive disorders—A longitudinal study of inpatient psychotherapy

BackgroundQuality of life (QoL) is substantially impaired in patients with anxiety disorders (AD) and depressive disorders (DD) and improvements in symptom burden after psychotherapy are not always paralleled by similar improvements in QoL. So far, little is known about treatment outcome in terms of...

Full description

Bibliographic Details
Main Authors: Marion Freidl, Melanie Wegerer, Zsuzsa Litvan, Daniel König, Rainer W. Alexandrowicz, Filipe Portela-Millinger, Maria Gruber
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.937194/full
_version_ 1828163157354348544
author Marion Freidl
Melanie Wegerer
Zsuzsa Litvan
Daniel König
Rainer W. Alexandrowicz
Filipe Portela-Millinger
Maria Gruber
author_facet Marion Freidl
Melanie Wegerer
Zsuzsa Litvan
Daniel König
Rainer W. Alexandrowicz
Filipe Portela-Millinger
Maria Gruber
author_sort Marion Freidl
collection DOAJ
description BackgroundQuality of life (QoL) is substantially impaired in patients with anxiety disorders (AD) and depressive disorders (DD) and improvements in symptom burden after psychotherapy are not always paralleled by similar improvements in QoL. So far, little is known about treatment outcome in terms of QoL and predictors of QoL improvements following inpatient psychotherapy with a focus on cognitive behavior therapy (CBT). The current study aimed at investigating the relationship between changes in symptoms and QoL across different life domains. Additionally, predictors of a positive treatment outcome were evaluated.Methods122 patients with AD and/or DD undergoing an 8-weeks inpatient CBT program completed self-report measures of psychopathological symptoms and QoL at pre- and post-treatment. Mixed effects models were used to investigate changes, a confirmatory factor analysis was applied to analyze the latent factor structure of the anxiety sensitivity index and binary logistic regression analyses were performed for predictors of QoL improvements.ResultsPatients showed moderate to strong decreases in anxious and depressive symptoms and moderate to strong improvements in general QoL, particularly in the psychological and physical QoL subdomains. Changes in symptom burden correlated most strongly with psychological and physical QoL. In addition, poor QoL before treatment and low levels of specific anxiety sensitivity symptoms (items 1 and 5) significantly predicted improvement in QoL.ConclusionPatients with poor QoL who are not as inhibited to openly express their anxious feelings particularly benefit from inpatient psychotherapy (individual and group) to improve their QoL. In contrast, our research suggests that patients who are too anxious to openly express their nervousness should receive additional social skills training, more focused treatment to build sufficient self-confidence to better engage in the treatment program.
first_indexed 2024-04-12T01:06:38Z
format Article
id doaj.art-83721cc2ba804a3f9a20a9b59e6411a2
institution Directory Open Access Journal
issn 1664-0640
language English
last_indexed 2024-04-12T01:06:38Z
publishDate 2022-12-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Psychiatry
spelling doaj.art-83721cc2ba804a3f9a20a9b59e6411a22022-12-22T03:54:15ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-12-011310.3389/fpsyt.2022.937194937194Determinants of quality of life improvements in anxiety and depressive disorders—A longitudinal study of inpatient psychotherapyMarion Freidl0Melanie Wegerer1Zsuzsa Litvan2Daniel König3Rainer W. Alexandrowicz4Filipe Portela-Millinger5Maria Gruber6Clinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, AustriaClinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, AustriaClinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, AustriaClinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, AustriaInstitute of Psychology, Alpen-Adria-University Klagenfurt, Klagenfurt, AustriaClinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, AustriaClinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, AustriaBackgroundQuality of life (QoL) is substantially impaired in patients with anxiety disorders (AD) and depressive disorders (DD) and improvements in symptom burden after psychotherapy are not always paralleled by similar improvements in QoL. So far, little is known about treatment outcome in terms of QoL and predictors of QoL improvements following inpatient psychotherapy with a focus on cognitive behavior therapy (CBT). The current study aimed at investigating the relationship between changes in symptoms and QoL across different life domains. Additionally, predictors of a positive treatment outcome were evaluated.Methods122 patients with AD and/or DD undergoing an 8-weeks inpatient CBT program completed self-report measures of psychopathological symptoms and QoL at pre- and post-treatment. Mixed effects models were used to investigate changes, a confirmatory factor analysis was applied to analyze the latent factor structure of the anxiety sensitivity index and binary logistic regression analyses were performed for predictors of QoL improvements.ResultsPatients showed moderate to strong decreases in anxious and depressive symptoms and moderate to strong improvements in general QoL, particularly in the psychological and physical QoL subdomains. Changes in symptom burden correlated most strongly with psychological and physical QoL. In addition, poor QoL before treatment and low levels of specific anxiety sensitivity symptoms (items 1 and 5) significantly predicted improvement in QoL.ConclusionPatients with poor QoL who are not as inhibited to openly express their anxious feelings particularly benefit from inpatient psychotherapy (individual and group) to improve their QoL. In contrast, our research suggests that patients who are too anxious to openly express their nervousness should receive additional social skills training, more focused treatment to build sufficient self-confidence to better engage in the treatment program.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.937194/fullquality of lifeinpatient psychotherapycognitive behavior therapyanxiety disorderdepressive disorderpredictors
spellingShingle Marion Freidl
Melanie Wegerer
Zsuzsa Litvan
Daniel König
Rainer W. Alexandrowicz
Filipe Portela-Millinger
Maria Gruber
Determinants of quality of life improvements in anxiety and depressive disorders—A longitudinal study of inpatient psychotherapy
Frontiers in Psychiatry
quality of life
inpatient psychotherapy
cognitive behavior therapy
anxiety disorder
depressive disorder
predictors
title Determinants of quality of life improvements in anxiety and depressive disorders—A longitudinal study of inpatient psychotherapy
title_full Determinants of quality of life improvements in anxiety and depressive disorders—A longitudinal study of inpatient psychotherapy
title_fullStr Determinants of quality of life improvements in anxiety and depressive disorders—A longitudinal study of inpatient psychotherapy
title_full_unstemmed Determinants of quality of life improvements in anxiety and depressive disorders—A longitudinal study of inpatient psychotherapy
title_short Determinants of quality of life improvements in anxiety and depressive disorders—A longitudinal study of inpatient psychotherapy
title_sort determinants of quality of life improvements in anxiety and depressive disorders a longitudinal study of inpatient psychotherapy
topic quality of life
inpatient psychotherapy
cognitive behavior therapy
anxiety disorder
depressive disorder
predictors
url https://www.frontiersin.org/articles/10.3389/fpsyt.2022.937194/full
work_keys_str_mv AT marionfreidl determinantsofqualityoflifeimprovementsinanxietyanddepressivedisordersalongitudinalstudyofinpatientpsychotherapy
AT melaniewegerer determinantsofqualityoflifeimprovementsinanxietyanddepressivedisordersalongitudinalstudyofinpatientpsychotherapy
AT zsuzsalitvan determinantsofqualityoflifeimprovementsinanxietyanddepressivedisordersalongitudinalstudyofinpatientpsychotherapy
AT danielkonig determinantsofqualityoflifeimprovementsinanxietyanddepressivedisordersalongitudinalstudyofinpatientpsychotherapy
AT rainerwalexandrowicz determinantsofqualityoflifeimprovementsinanxietyanddepressivedisordersalongitudinalstudyofinpatientpsychotherapy
AT filipeportelamillinger determinantsofqualityoflifeimprovementsinanxietyanddepressivedisordersalongitudinalstudyofinpatientpsychotherapy
AT mariagruber determinantsofqualityoflifeimprovementsinanxietyanddepressivedisordersalongitudinalstudyofinpatientpsychotherapy