Predictive value of color doppler neuro-sonography for the development of neurological sequels in newborn infants with hypoxic ischemic encephalopathy
Background/Aim. The use of color Doppler neurosonography (cD-US) allows simultaneous examination of parenchymal and vascular cerebral structures. Evaluation of cerebral blood flow velocities (CBFV) and vascular resistance are important in assessment of cerebral circulation in neonates with hypoxi...
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| Format: | Article |
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Military Health Department, Ministry of Defance, Serbia
2011-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2011/0042-84501110825V.pdf |
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| author | Vasiljević Brankica Maglajlić-Đukić Svjetlana Stanković Sanja Lutovac Dragana Gojnić Miroslava |
| author_facet | Vasiljević Brankica Maglajlić-Đukić Svjetlana Stanković Sanja Lutovac Dragana Gojnić Miroslava |
| author_sort | Vasiljević Brankica |
| collection | DOAJ |
| description | Background/Aim. The use of color Doppler neurosonography (cD-US) allows simultaneous examination of parenchymal and vascular cerebral structures. Evaluation of cerebral blood flow velocities (CBFV) and vascular resistance are important in assessment of cerebral circulation in neonates with hypoxic ischemic encephalopathy (HIE). The aim of this study was to evaluate the predictive value of cD-US for abnormal neurodevelopmental outcome in the neonates with HIE. Methods. A total of 90 neonates (>32 weeks gestational age) with HIE were enrolled prospectively. All the neonates with HIE were categorized into three grades according to the Sarnat and Sarnat clinical staging system: mild HIE, moderate HIE, and severe HIE. cD-US was performed simultaneously during the first 24 h of life. Neurodevelopment outcome was assessed at 12 months of age in all the neonates. Resluts. The values of CBFV and the values of index resistance (RI) correlated with the severity of HIE (p < 0.0001) and subsequent neurodevelopmental outcome (p < 0.001). We detected a significant difference in values of CBFV and in values of RI between preterm and full-term neonates (p < 0.01). The cut-off value of RI for poor neurodevelopmental outcomes was 0.81. Conclusions. cD-US could be very useful and safe diagnostic tool for assessing severity of HIE and subsequent adverse neurodevelopmental outcome. |
| first_indexed | 2024-12-11T01:58:31Z |
| format | Article |
| id | doaj.art-8374927dbbbf4adfb1b707393397b6d5 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 |
| language | English |
| last_indexed | 2024-12-11T01:58:31Z |
| publishDate | 2011-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-8374927dbbbf4adfb1b707393397b6d52022-12-22T01:24:33ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502011-01-01681082583110.2298/VSP1110825VPredictive value of color doppler neuro-sonography for the development of neurological sequels in newborn infants with hypoxic ischemic encephalopathyVasiljević BrankicaMaglajlić-Đukić SvjetlanaStanković SanjaLutovac DraganaGojnić MiroslavaBackground/Aim. The use of color Doppler neurosonography (cD-US) allows simultaneous examination of parenchymal and vascular cerebral structures. Evaluation of cerebral blood flow velocities (CBFV) and vascular resistance are important in assessment of cerebral circulation in neonates with hypoxic ischemic encephalopathy (HIE). The aim of this study was to evaluate the predictive value of cD-US for abnormal neurodevelopmental outcome in the neonates with HIE. Methods. A total of 90 neonates (>32 weeks gestational age) with HIE were enrolled prospectively. All the neonates with HIE were categorized into three grades according to the Sarnat and Sarnat clinical staging system: mild HIE, moderate HIE, and severe HIE. cD-US was performed simultaneously during the first 24 h of life. Neurodevelopment outcome was assessed at 12 months of age in all the neonates. Resluts. The values of CBFV and the values of index resistance (RI) correlated with the severity of HIE (p < 0.0001) and subsequent neurodevelopmental outcome (p < 0.001). We detected a significant difference in values of CBFV and in values of RI between preterm and full-term neonates (p < 0.01). The cut-off value of RI for poor neurodevelopmental outcomes was 0.81. Conclusions. cD-US could be very useful and safe diagnostic tool for assessing severity of HIE and subsequent adverse neurodevelopmental outcome.http://www.doiserbia.nb.rs/img/doi/0042-8450/2011/0042-84501110825V.pdfultrasonography, doppler, transcranialinfant, newbornhypoxia-ischemia, brainprognosispreterm birthcerebral palsy |
| spellingShingle | Vasiljević Brankica Maglajlić-Đukić Svjetlana Stanković Sanja Lutovac Dragana Gojnić Miroslava Predictive value of color doppler neuro-sonography for the development of neurological sequels in newborn infants with hypoxic ischemic encephalopathy Vojnosanitetski Pregled ultrasonography, doppler, transcranial infant, newborn hypoxia-ischemia, brain prognosis preterm birth cerebral palsy |
| title | Predictive value of color doppler neuro-sonography for the development of neurological sequels in newborn infants with hypoxic ischemic encephalopathy |
| title_full | Predictive value of color doppler neuro-sonography for the development of neurological sequels in newborn infants with hypoxic ischemic encephalopathy |
| title_fullStr | Predictive value of color doppler neuro-sonography for the development of neurological sequels in newborn infants with hypoxic ischemic encephalopathy |
| title_full_unstemmed | Predictive value of color doppler neuro-sonography for the development of neurological sequels in newborn infants with hypoxic ischemic encephalopathy |
| title_short | Predictive value of color doppler neuro-sonography for the development of neurological sequels in newborn infants with hypoxic ischemic encephalopathy |
| title_sort | predictive value of color doppler neuro sonography for the development of neurological sequels in newborn infants with hypoxic ischemic encephalopathy |
| topic | ultrasonography, doppler, transcranial infant, newborn hypoxia-ischemia, brain prognosis preterm birth cerebral palsy |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2011/0042-84501110825V.pdf |
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