Existence of Similar <i>Leptospira</i> Serovars among Dog Keepers and Their Respective Dogs in Mwanza, Tanzania, the Need for a One Health Approach to Control Measures
This study investigated seroepidemiology of <i>Leptospira</i> serovars among the dog keepers and their dogs in the city of Mwanza, Tanzania. A total of 205 dog keepers and 414 dogs were tested for <i>Leptospira</i> antibodies using a microscopic agglutination test (MAT). The...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
|
| Series: | Pathogens |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-0817/10/5/609 |
| _version_ | 1827692398279393280 |
|---|---|
| author | Betrand Msemwa Mariam M. Mirambo Vitus Silago Juma M. Samson Khadija S. Majid Ginethon Mhamphi Joseph Genchwere Subira S. Mwakabumbe Elifuraha B. Mngumi Georgies Mgode Stephen E. Mshana |
| author_facet | Betrand Msemwa Mariam M. Mirambo Vitus Silago Juma M. Samson Khadija S. Majid Ginethon Mhamphi Joseph Genchwere Subira S. Mwakabumbe Elifuraha B. Mngumi Georgies Mgode Stephen E. Mshana |
| author_sort | Betrand Msemwa |
| collection | DOAJ |
| description | This study investigated seroepidemiology of <i>Leptospira</i> serovars among the dog keepers and their dogs in the city of Mwanza, Tanzania. A total of 205 dog keepers and 414 dogs were tested for <i>Leptospira</i> antibodies using a microscopic agglutination test (MAT). The median age of the dog keepers was 26 (inter quartile range (IQR): 17–40) years and median duration of keeping dogs was 36 (IQR: 24–120) months. The seropositivity of <i>Leptospira</i> antibodies was (33/205 (16.1%, 95% CI: 11.0–21.1) among dog keepers and (66/414 (15.9%, 95% CI: 12.4–19.4) among dogs, <i>p</i> = 0.4745. Among the serovars tested (Sokoine, Grippotyphosa, Kenya, Pomona and Hebdomadis), the most prevalent serovar was Sokoine in both dog keepers and their dogs (93.9% (31/33) vs. and 65.1% (43/66), <i>p</i> = 0.009). Thirty-one out of thirty-three seropositive dog keepers (93.9%) had dogs positive for <i>Leptospira</i> antibodies with 28 (84.9%) having similar serovars with their respective seropositive dogs. Having tertiary education (AOR: 0.24, 95% CI: 0.07–0.84, <i>p</i> = 0.026) independently protected individuals from being <i>Leptospira</i> seropositive. More than three quarters of dog keepers had similar serovars as their dogs, necessitating one health approach to control measures in endemic areas. |
| first_indexed | 2024-03-10T11:22:05Z |
| format | Article |
| id | doaj.art-837635807dd943df80a39e9eb6c2c485 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T11:22:05Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-837635807dd943df80a39e9eb6c2c4852023-11-21T19:58:58ZengMDPI AGPathogens2076-08172021-05-0110560910.3390/pathogens10050609Existence of Similar <i>Leptospira</i> Serovars among Dog Keepers and Their Respective Dogs in Mwanza, Tanzania, the Need for a One Health Approach to Control MeasuresBetrand Msemwa0Mariam M. Mirambo1Vitus Silago2Juma M. Samson3Khadija S. Majid4Ginethon Mhamphi5Joseph Genchwere6Subira S. Mwakabumbe7Elifuraha B. Mngumi8Georgies Mgode9Stephen E. Mshana10Department of Medical Laboratory Sciences, Institute of Allied Health Sciences, Catholic University of Health and Allied Sciences, Bugando, Mwanza P.O. Box 1464, TanzaniaDepartment of Microbiology and Immunology, Catholic University of Health and Allied Sciences, Bugando, Mwanza P.O. Box 1464, TanzaniaDepartment of Microbiology and Immunology, Catholic University of Health and Allied Sciences, Bugando, Mwanza P.O. Box 1464, TanzaniaDepartment of Microbiology and Immunology, Catholic University of Health and Allied Sciences, Bugando, Mwanza P.O. Box 1464, TanzaniaDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, Morogoro P.O. Box 3021, TanzaniaSUA Pest Management Centre (SPMC), Sokoine University of Agriculture, Morogoro P.O. Box 3110, TanzaniaTanzania Veterinary Laboratory Agency (TVLA), Lake Zone, Ministry of Livestock and Fisheries, Mwanza P.O. Box 129, TanzaniaVeterinary Investigation Centre (VIC), Lake Zone, Ministry of Livestock and Fisheries, Mwanza P.O. Box 129, TanzaniaDepartment of Veterinary Anatomy and Pathology, School of Biomedical Sciences, Sokoine University of Agriculture, Morogoro P.O. Box 3016, TanzaniaSUA Pest Management Centre (SPMC), Sokoine University of Agriculture, Morogoro P.O. Box 3110, TanzaniaDepartment of Microbiology and Immunology, Catholic University of Health and Allied Sciences, Bugando, Mwanza P.O. Box 1464, TanzaniaThis study investigated seroepidemiology of <i>Leptospira</i> serovars among the dog keepers and their dogs in the city of Mwanza, Tanzania. A total of 205 dog keepers and 414 dogs were tested for <i>Leptospira</i> antibodies using a microscopic agglutination test (MAT). The median age of the dog keepers was 26 (inter quartile range (IQR): 17–40) years and median duration of keeping dogs was 36 (IQR: 24–120) months. The seropositivity of <i>Leptospira</i> antibodies was (33/205 (16.1%, 95% CI: 11.0–21.1) among dog keepers and (66/414 (15.9%, 95% CI: 12.4–19.4) among dogs, <i>p</i> = 0.4745. Among the serovars tested (Sokoine, Grippotyphosa, Kenya, Pomona and Hebdomadis), the most prevalent serovar was Sokoine in both dog keepers and their dogs (93.9% (31/33) vs. and 65.1% (43/66), <i>p</i> = 0.009). Thirty-one out of thirty-three seropositive dog keepers (93.9%) had dogs positive for <i>Leptospira</i> antibodies with 28 (84.9%) having similar serovars with their respective seropositive dogs. Having tertiary education (AOR: 0.24, 95% CI: 0.07–0.84, <i>p</i> = 0.026) independently protected individuals from being <i>Leptospira</i> seropositive. More than three quarters of dog keepers had similar serovars as their dogs, necessitating one health approach to control measures in endemic areas.https://www.mdpi.com/2076-0817/10/5/609Mwanza<i>Leptospira</i> antibodiesmicroscopic agglutination (MAT)serovar Sokoinezoonotic disease |
| spellingShingle | Betrand Msemwa Mariam M. Mirambo Vitus Silago Juma M. Samson Khadija S. Majid Ginethon Mhamphi Joseph Genchwere Subira S. Mwakabumbe Elifuraha B. Mngumi Georgies Mgode Stephen E. Mshana Existence of Similar <i>Leptospira</i> Serovars among Dog Keepers and Their Respective Dogs in Mwanza, Tanzania, the Need for a One Health Approach to Control Measures Pathogens Mwanza <i>Leptospira</i> antibodies microscopic agglutination (MAT) serovar Sokoine zoonotic disease |
| title | Existence of Similar <i>Leptospira</i> Serovars among Dog Keepers and Their Respective Dogs in Mwanza, Tanzania, the Need for a One Health Approach to Control Measures |
| title_full | Existence of Similar <i>Leptospira</i> Serovars among Dog Keepers and Their Respective Dogs in Mwanza, Tanzania, the Need for a One Health Approach to Control Measures |
| title_fullStr | Existence of Similar <i>Leptospira</i> Serovars among Dog Keepers and Their Respective Dogs in Mwanza, Tanzania, the Need for a One Health Approach to Control Measures |
| title_full_unstemmed | Existence of Similar <i>Leptospira</i> Serovars among Dog Keepers and Their Respective Dogs in Mwanza, Tanzania, the Need for a One Health Approach to Control Measures |
| title_short | Existence of Similar <i>Leptospira</i> Serovars among Dog Keepers and Their Respective Dogs in Mwanza, Tanzania, the Need for a One Health Approach to Control Measures |
| title_sort | existence of similar i leptospira i serovars among dog keepers and their respective dogs in mwanza tanzania the need for a one health approach to control measures |
| topic | Mwanza <i>Leptospira</i> antibodies microscopic agglutination (MAT) serovar Sokoine zoonotic disease |
| url | https://www.mdpi.com/2076-0817/10/5/609 |
| work_keys_str_mv | AT betrandmsemwa existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures AT mariammmirambo existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures AT vitussilago existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures AT jumamsamson existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures AT khadijasmajid existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures AT ginethonmhamphi existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures AT josephgenchwere existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures AT subirasmwakabumbe existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures AT elifurahabmngumi existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures AT georgiesmgode existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures AT stephenemshana existenceofsimilarileptospiraiserovarsamongdogkeepersandtheirrespectivedogsinmwanzatanzaniatheneedforaonehealthapproachtocontrolmeasures |