A New Approach of Phonocardiogram Analysis for Screening Some of Cardio-vascular Diseases Based on Deep Learning

Background: Cardiovascular diseases are one of the leading causes of death worldwide. Therefore, early diagnosis of heart disease, evaluation of cardiovascular system using cardiac hearing and Phonocardiogram (PCG) analysis which is a low cost, non-invasive, rapid method, and automatic screening of...

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Main Authors: Ehsan Mohammadi, Saeed Kermani, Mahdi Nourian-Zavareh, Alale Zare, Hamed Aghapanah-Roudsari, Maryam Samieinasab, Hamid Sanei
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2022-04-01
Series:مجله دانشکده پزشکی اصفهان
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Online Access:https://jims.mui.ac.ir/article_16314_409703be8e0bdb09d476f63da82cc924.pdf
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author Ehsan Mohammadi
Saeed Kermani
Mahdi Nourian-Zavareh
Alale Zare
Hamed Aghapanah-Roudsari
Maryam Samieinasab
Hamid Sanei
author_facet Ehsan Mohammadi
Saeed Kermani
Mahdi Nourian-Zavareh
Alale Zare
Hamed Aghapanah-Roudsari
Maryam Samieinasab
Hamid Sanei
author_sort Ehsan Mohammadi
collection DOAJ
description Background: Cardiovascular diseases are one of the leading causes of death worldwide. Therefore, early diagnosis of heart disease, evaluation of cardiovascular system using cardiac hearing and Phonocardiogram (PCG) analysis which is a low cost, non-invasive, rapid method, and automatic screening of cardiovascular patients in remote areas is crucial. The aim of this study is to present a new method for screening heart patients based on signal processing (PCG) that is cheap and fast and has sufficient accuracy.Methods: In this study, for screening 2062 labeled PCG signals, by extracting new features and applying them in 1- Random forest network 2- K-nearest neighbors 3- Decision tree 4- Linear discriminant analysis 5- Logistic regression and 6- Deep neural network, six different models were constructed and each of them was evaluated by k fold cross-validation method (K = 10). The test data were applied to the mentioned models and based on the outputs of these models, three indicators of accuracy, sensitivity and specificity were calculated. We showed and developed a new solution in differentiating and screening some heart patients from healthy individuals using PCG analysis.Findings: Evaluation on the mentioned models was calculated by the three indicators, repeated 5 times and their mean and variance values were calculated. The highest sensitivity value is related to deep neural network (DNN) with sensitivity of 96.4 ± 0.14 and accuracy of 93.4 ± 0.11.Conclusion: The new differential features along with the success of the proposed deep neural network in differentiating and screening between PCGs of healthy individuals and heart patients, shows the efficiency of the proposed algorithm. This method can be further improved with simultaneous multimodal classifier and the application of the voting rule.
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spelling doaj.art-83794cc8decf4008bbdf52ff110df05c2023-09-02T11:40:52ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2022-04-014066110911410.48305/jims.2022.1631416314A New Approach of Phonocardiogram Analysis for Screening Some of Cardio-vascular Diseases Based on Deep LearningEhsan Mohammadi0Saeed Kermani1Mahdi Nourian-Zavareh2Alale Zare3Hamed Aghapanah-Roudsari4Maryam Samieinasab5Hamid Sanei6PhD Student, Department of Bioelectrics and Biomedical Engineering, Student Research Committee, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, IranProfessor, Department of Bioelectrics and Biomedical Engineering, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, IranMSc Graduate, Department of Bioelectrics and Biomedical Engineering, Student Research Committee, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, IranMSc Graduate, Student Research Committee, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran5- PhD Student, Department of Bioelectrics and Biomedical Engineering, Student Research Committee, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, IranPhD Student, Department of Bioelectrics and Biomedical Engineering, Student Research Committee, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, IranProfessor of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranBackground: Cardiovascular diseases are one of the leading causes of death worldwide. Therefore, early diagnosis of heart disease, evaluation of cardiovascular system using cardiac hearing and Phonocardiogram (PCG) analysis which is a low cost, non-invasive, rapid method, and automatic screening of cardiovascular patients in remote areas is crucial. The aim of this study is to present a new method for screening heart patients based on signal processing (PCG) that is cheap and fast and has sufficient accuracy.Methods: In this study, for screening 2062 labeled PCG signals, by extracting new features and applying them in 1- Random forest network 2- K-nearest neighbors 3- Decision tree 4- Linear discriminant analysis 5- Logistic regression and 6- Deep neural network, six different models were constructed and each of them was evaluated by k fold cross-validation method (K = 10). The test data were applied to the mentioned models and based on the outputs of these models, three indicators of accuracy, sensitivity and specificity were calculated. We showed and developed a new solution in differentiating and screening some heart patients from healthy individuals using PCG analysis.Findings: Evaluation on the mentioned models was calculated by the three indicators, repeated 5 times and their mean and variance values were calculated. The highest sensitivity value is related to deep neural network (DNN) with sensitivity of 96.4 ± 0.14 and accuracy of 93.4 ± 0.11.Conclusion: The new differential features along with the success of the proposed deep neural network in differentiating and screening between PCGs of healthy individuals and heart patients, shows the efficiency of the proposed algorithm. This method can be further improved with simultaneous multimodal classifier and the application of the voting rule.https://jims.mui.ac.ir/article_16314_409703be8e0bdb09d476f63da82cc924.pdfcardiovascular diagnostic technicdeep learningdiagnostic screening programscardiovascular diseases
spellingShingle Ehsan Mohammadi
Saeed Kermani
Mahdi Nourian-Zavareh
Alale Zare
Hamed Aghapanah-Roudsari
Maryam Samieinasab
Hamid Sanei
A New Approach of Phonocardiogram Analysis for Screening Some of Cardio-vascular Diseases Based on Deep Learning
مجله دانشکده پزشکی اصفهان
cardiovascular diagnostic technic
deep learning
diagnostic screening programs
cardiovascular diseases
title A New Approach of Phonocardiogram Analysis for Screening Some of Cardio-vascular Diseases Based on Deep Learning
title_full A New Approach of Phonocardiogram Analysis for Screening Some of Cardio-vascular Diseases Based on Deep Learning
title_fullStr A New Approach of Phonocardiogram Analysis for Screening Some of Cardio-vascular Diseases Based on Deep Learning
title_full_unstemmed A New Approach of Phonocardiogram Analysis for Screening Some of Cardio-vascular Diseases Based on Deep Learning
title_short A New Approach of Phonocardiogram Analysis for Screening Some of Cardio-vascular Diseases Based on Deep Learning
title_sort new approach of phonocardiogram analysis for screening some of cardio vascular diseases based on deep learning
topic cardiovascular diagnostic technic
deep learning
diagnostic screening programs
cardiovascular diseases
url https://jims.mui.ac.ir/article_16314_409703be8e0bdb09d476f63da82cc924.pdf
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