Apoptosis-like cell death upon kinetoplastid induction by compounds isolated from the brown algae Dictyota spiralis

Apoptosis-like cell death upon kinetoplastid induction by compounds isolated from the brown algae Dictyota spiralis

Abstract Background The in vitro activity of the brown seaweed Dictyota spiralis against both Leishmania amazonensis and Trypanosoma cruzi was evaluated in a previous study. Processing by bio-guided fractionation resulted in the isolation of three active compounds, classified as diterpenes. In the p...

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Bibliographic Details
Main Authors: Olfa Chiboub, Ines Sifaoui, Manef Abderrabba, Mondher Mejri, José J. Fernández, Ana R. Díaz-Marrero, Jacob Lorenzo-Morales, José E. Piñero
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Parasites & Vectors
Subjects:
T. cruzi
L. amazonensis
Diterpenes
Marine compounds
Antikinetoplastid
Apoptosis-like
Online Access:https://doi.org/10.1186/s13071-021-04693-7

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