Pyroptotic gasdermin exists in Mollusca and is vital to eliminating bacterial infection

Pyroptotic gasdermin exists in Mollusca and is vital to eliminating bacterial infection

Summary: Gasdermin (GSDM) is a family of proteins that execute pyroptosis in vertebrate. In invertebrate, pyroptotic GSDM was documented only in coral. Recent studies identified abundant GSDM structural homologs in Mollusca, but their functions are unclear. Herein, we report a functional GSDM from P...

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Bibliographic Details
Main Authors: Kunpeng Qin, Shuai Jiang, Hang Xu, Zihao Yuan, Li Sun
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
CP: Immunology
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723004254

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