Crystal structure and Hirshfeld surface analysis of N-(2,6-dimethylphenyl)-2-[3-hydroxy-2-oxo-3-(2-oxopropyl)indolin-1-yl]acetamide
The cup-shaped conformation of the title molecule, C21H22N2O4, is largely determined by an intramolecular N—H...O hydrogen bond. In the crystal, double layers of molecules are formed by O—H...O and C—H...O hydrogen bonds. A Hirshfeld surface analysis was performed, which confirms the regions that ar...
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2022-09-01
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| Series: | Acta Crystallographica Section E: Crystallographic Communications |
| Subjects: | |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S2056989022007848 |
| _version_ | 1798037255161380864 |
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| author | Intissar Nchioua Abdulsalam Alsubari Joel T. Mague Youssef Ramli |
| author_facet | Intissar Nchioua Abdulsalam Alsubari Joel T. Mague Youssef Ramli |
| author_sort | Intissar Nchioua |
| collection | DOAJ |
| description | The cup-shaped conformation of the title molecule, C21H22N2O4, is largely determined by an intramolecular N—H...O hydrogen bond. In the crystal, double layers of molecules are formed by O—H...O and C—H...O hydrogen bonds. A Hirshfeld surface analysis was performed, which confirms the regions that are active for intermolecular interactions. |
| first_indexed | 2024-04-11T21:24:06Z |
| format | Article |
| id | doaj.art-838476e09dce446fbce0bbbaf1699630 |
| institution | Directory Open Access Journal |
| issn | 2056-9890 |
| language | English |
| last_indexed | 2024-04-11T21:24:06Z |
| publishDate | 2022-09-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | Acta Crystallographica Section E: Crystallographic Communications |
| spelling | doaj.art-838476e09dce446fbce0bbbaf16996302022-12-22T04:02:31ZengInternational Union of CrystallographyActa Crystallographica Section E: Crystallographic Communications2056-98902022-09-0178992292510.1107/S2056989022007848zn2021Crystal structure and Hirshfeld surface analysis of N-(2,6-dimethylphenyl)-2-[3-hydroxy-2-oxo-3-(2-oxopropyl)indolin-1-yl]acetamideIntissar Nchioua0Abdulsalam Alsubari1Joel T. Mague2Youssef Ramli3Laboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, MoroccoLaboratory of Medicinal Chemistry, Faculty of Clinical Pharmacy, 21 September University, YemenDepartment of Chemistry, 8 Tulane University, New Orleans, LA 70118, USALaboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, MoroccoThe cup-shaped conformation of the title molecule, C21H22N2O4, is largely determined by an intramolecular N—H...O hydrogen bond. In the crystal, double layers of molecules are formed by O—H...O and C—H...O hydrogen bonds. A Hirshfeld surface analysis was performed, which confirms the regions that are active for intermolecular interactions.http://scripts.iucr.org/cgi-bin/paper?S2056989022007848crystal structurehydrogen bondindolearylacetamidehirshfeld surface |
| spellingShingle | Intissar Nchioua Abdulsalam Alsubari Joel T. Mague Youssef Ramli Crystal structure and Hirshfeld surface analysis of N-(2,6-dimethylphenyl)-2-[3-hydroxy-2-oxo-3-(2-oxopropyl)indolin-1-yl]acetamide Acta Crystallographica Section E: Crystallographic Communications crystal structure hydrogen bond indole arylacetamide hirshfeld surface |
| title | Crystal structure and Hirshfeld surface analysis of N-(2,6-dimethylphenyl)-2-[3-hydroxy-2-oxo-3-(2-oxopropyl)indolin-1-yl]acetamide |
| title_full | Crystal structure and Hirshfeld surface analysis of N-(2,6-dimethylphenyl)-2-[3-hydroxy-2-oxo-3-(2-oxopropyl)indolin-1-yl]acetamide |
| title_fullStr | Crystal structure and Hirshfeld surface analysis of N-(2,6-dimethylphenyl)-2-[3-hydroxy-2-oxo-3-(2-oxopropyl)indolin-1-yl]acetamide |
| title_full_unstemmed | Crystal structure and Hirshfeld surface analysis of N-(2,6-dimethylphenyl)-2-[3-hydroxy-2-oxo-3-(2-oxopropyl)indolin-1-yl]acetamide |
| title_short | Crystal structure and Hirshfeld surface analysis of N-(2,6-dimethylphenyl)-2-[3-hydroxy-2-oxo-3-(2-oxopropyl)indolin-1-yl]acetamide |
| title_sort | crystal structure and hirshfeld surface analysis of n 2 6 dimethylphenyl 2 3 hydroxy 2 oxo 3 2 oxopropyl indolin 1 yl acetamide |
| topic | crystal structure hydrogen bond indole arylacetamide hirshfeld surface |
| url | http://scripts.iucr.org/cgi-bin/paper?S2056989022007848 |
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