Irreversible electroporation of hepatocellular carcinoma: the role of ultrasonography
Irreversible electroporation (IRE) is a novel form of soft tissue ablation therapy that uses high-current electrical pulses to induce the formation of pores in the cell membrane, leading to cell death. Although outcome data for the ablation of hepatocellular carcinoma (HCC) by IRE are limited, early...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Society of Ultrasound in Medicine
2020-07-01
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| Series: | Ultrasonography |
| Subjects: | |
| Online Access: | http://www.e-ultrasonography.org/upload/usg-20023.pdf |
| _version_ | 1828874389891842048 |
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| author | Katsutoshi Sugimoto Masakazu Abe Yu Yoshimasu Hirohito Takeuchi Yoshitaka Kasai Takao Itoi |
| author_facet | Katsutoshi Sugimoto Masakazu Abe Yu Yoshimasu Hirohito Takeuchi Yoshitaka Kasai Takao Itoi |
| author_sort | Katsutoshi Sugimoto |
| collection | DOAJ |
| description | Irreversible electroporation (IRE) is a novel form of soft tissue ablation therapy that uses high-current electrical pulses to induce the formation of pores in the cell membrane, leading to cell death. Although outcome data for the ablation of hepatocellular carcinoma (HCC) by IRE are limited, early results are encouraging and may suggest equivalency to the outcomes achieved by thermal ablation methods such as radiofrequency ablation (RFA) and microwave ablation (MWA). However, IRE can be a challenging and very time-consuming procedure compared to RFA and MWA. In this review article, we not only evaluate the efficacy and safety of IRE for the treatment of HCC, but also discuss imaging guidance, ablation monitoring, and endpoint assessment, with a particular focus on ultrasonography. |
| first_indexed | 2024-12-13T07:37:26Z |
| format | Article |
| id | doaj.art-83849da74f4940a6a026900e5e70a3eb |
| institution | Directory Open Access Journal |
| issn | 2288-5919 2288-5943 |
| language | English |
| last_indexed | 2024-12-13T07:37:26Z |
| publishDate | 2020-07-01 |
| publisher | Korean Society of Ultrasound in Medicine |
| record_format | Article |
| series | Ultrasonography |
| spelling | doaj.art-83849da74f4940a6a026900e5e70a3eb2022-12-21T23:55:03ZengKorean Society of Ultrasound in MedicineUltrasonography2288-59192288-59432020-07-0139322923710.14366/usg.200231104Irreversible electroporation of hepatocellular carcinoma: the role of ultrasonographyKatsutoshi SugimotoMasakazu AbeYu YoshimasuHirohito TakeuchiYoshitaka KasaiTakao ItoiIrreversible electroporation (IRE) is a novel form of soft tissue ablation therapy that uses high-current electrical pulses to induce the formation of pores in the cell membrane, leading to cell death. Although outcome data for the ablation of hepatocellular carcinoma (HCC) by IRE are limited, early results are encouraging and may suggest equivalency to the outcomes achieved by thermal ablation methods such as radiofrequency ablation (RFA) and microwave ablation (MWA). However, IRE can be a challenging and very time-consuming procedure compared to RFA and MWA. In this review article, we not only evaluate the efficacy and safety of IRE for the treatment of HCC, but also discuss imaging guidance, ablation monitoring, and endpoint assessment, with a particular focus on ultrasonography.http://www.e-ultrasonography.org/upload/usg-20023.pdfirreversible electroporationhepatocellular carcinomaultrasonographyablation |
| spellingShingle | Katsutoshi Sugimoto Masakazu Abe Yu Yoshimasu Hirohito Takeuchi Yoshitaka Kasai Takao Itoi Irreversible electroporation of hepatocellular carcinoma: the role of ultrasonography Ultrasonography irreversible electroporation hepatocellular carcinoma ultrasonography ablation |
| title | Irreversible electroporation of hepatocellular carcinoma: the role of ultrasonography |
| title_full | Irreversible electroporation of hepatocellular carcinoma: the role of ultrasonography |
| title_fullStr | Irreversible electroporation of hepatocellular carcinoma: the role of ultrasonography |
| title_full_unstemmed | Irreversible electroporation of hepatocellular carcinoma: the role of ultrasonography |
| title_short | Irreversible electroporation of hepatocellular carcinoma: the role of ultrasonography |
| title_sort | irreversible electroporation of hepatocellular carcinoma the role of ultrasonography |
| topic | irreversible electroporation hepatocellular carcinoma ultrasonography ablation |
| url | http://www.e-ultrasonography.org/upload/usg-20023.pdf |
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