Effects of chitosan and TiO2 nanoparticles on the antibacterial property and ability to self-healing of cracks and retrieve mechanical characteristics of dental composites
The aim of this study was to improve the self-healing properties of dental nanocomposite using nanoparticles of TiO2 and chitosan. We evaluated flexural and compressive strength, crack-healing, and self-healing lifespan after 3 months of water aging. The effect of the developed composite on cell via...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024037654 |
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| author | Reza Ravandi Saeed Zeinali Heris Salar Hemmati Marziyeh Aghazadeh Soodabeh Davaran Nima Abdyazdani |
| author_facet | Reza Ravandi Saeed Zeinali Heris Salar Hemmati Marziyeh Aghazadeh Soodabeh Davaran Nima Abdyazdani |
| author_sort | Reza Ravandi |
| collection | DOAJ |
| description | The aim of this study was to improve the self-healing properties of dental nanocomposite using nanoparticles of TiO2 and chitosan. We evaluated flexural and compressive strength, crack-healing, and self-healing lifespan after 3 months of water aging. The effect of the developed composite on cell viability and toxicity was assessed by an MTT assay on human alveolar basal epithelial cells (A549 cell line). The nanocomposite included 7.5 wt% polyurea-formaldehyde (PUF) and 0, 0.5, and 1 wt% n-TiO2 and chitosan. After the fracture, the samples were put in a mold for 1–90 days to enable healing. Then, the fracture toughness of the healed nanocomposites and the healing yield were measured. The flexural strength of the nanocomposite improved by adding 0.5 wt% n-TiO2, while the compressive strength increased after adding 0.5 wt% chitosan (p > 0.1). When these two materials were used simultaneously, the flexural strength was improved by around 2%; however, the compressive strength was unaffected. Compared to the other sample, the nanocomposite with 0.5 wt% n-TiO2 and chitosan had higher KIC-healing and self-healing efficiency. Self-healing efficacy had no significant effect of water aging over 90 days compared to one day (p > 0.1), demonstrating that the PUF nanocapsules were not damaged. |
| first_indexed | 2024-04-24T13:49:26Z |
| format | Article |
| id | doaj.art-83898a0dfc3449ebad2667cb48e041f9 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-24T13:49:26Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-83898a0dfc3449ebad2667cb48e041f92024-04-04T05:05:45ZengElsevierHeliyon2405-84402024-03-01106e27734Effects of chitosan and TiO2 nanoparticles on the antibacterial property and ability to self-healing of cracks and retrieve mechanical characteristics of dental compositesReza Ravandi0Saeed Zeinali Heris1Salar Hemmati2Marziyeh Aghazadeh3Soodabeh Davaran4Nima Abdyazdani5Faculty of Chemical and Petroleum Engineering, University of Tabriz, Tabriz, IranFaculty of Chemical and Petroleum Engineering, University of Tabriz, Tabriz, Iran; Corresponding author.Drug Applied Research Center, Tabriz University of Medical Sciences, 65811, Tabriz, IranStem Cell Research Centre and Department of Oral Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Medical Nanotechnology, Faculty of Advanced Medical Science, Tabriz University of Medical Sciences, Golgasht St, Tabriz, IranStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, IranThe aim of this study was to improve the self-healing properties of dental nanocomposite using nanoparticles of TiO2 and chitosan. We evaluated flexural and compressive strength, crack-healing, and self-healing lifespan after 3 months of water aging. The effect of the developed composite on cell viability and toxicity was assessed by an MTT assay on human alveolar basal epithelial cells (A549 cell line). The nanocomposite included 7.5 wt% polyurea-formaldehyde (PUF) and 0, 0.5, and 1 wt% n-TiO2 and chitosan. After the fracture, the samples were put in a mold for 1–90 days to enable healing. Then, the fracture toughness of the healed nanocomposites and the healing yield were measured. The flexural strength of the nanocomposite improved by adding 0.5 wt% n-TiO2, while the compressive strength increased after adding 0.5 wt% chitosan (p > 0.1). When these two materials were used simultaneously, the flexural strength was improved by around 2%; however, the compressive strength was unaffected. Compared to the other sample, the nanocomposite with 0.5 wt% n-TiO2 and chitosan had higher KIC-healing and self-healing efficiency. Self-healing efficacy had no significant effect of water aging over 90 days compared to one day (p > 0.1), demonstrating that the PUF nanocapsules were not damaged.http://www.sciencedirect.com/science/article/pii/S2405844024037654Dental compositesChitosan and TiO2 nanoparticlesSelf-healingCytotoxicity |
| spellingShingle | Reza Ravandi Saeed Zeinali Heris Salar Hemmati Marziyeh Aghazadeh Soodabeh Davaran Nima Abdyazdani Effects of chitosan and TiO2 nanoparticles on the antibacterial property and ability to self-healing of cracks and retrieve mechanical characteristics of dental composites Heliyon Dental composites Chitosan and TiO2 nanoparticles Self-healing Cytotoxicity |
| title | Effects of chitosan and TiO2 nanoparticles on the antibacterial property and ability to self-healing of cracks and retrieve mechanical characteristics of dental composites |
| title_full | Effects of chitosan and TiO2 nanoparticles on the antibacterial property and ability to self-healing of cracks and retrieve mechanical characteristics of dental composites |
| title_fullStr | Effects of chitosan and TiO2 nanoparticles on the antibacterial property and ability to self-healing of cracks and retrieve mechanical characteristics of dental composites |
| title_full_unstemmed | Effects of chitosan and TiO2 nanoparticles on the antibacterial property and ability to self-healing of cracks and retrieve mechanical characteristics of dental composites |
| title_short | Effects of chitosan and TiO2 nanoparticles on the antibacterial property and ability to self-healing of cracks and retrieve mechanical characteristics of dental composites |
| title_sort | effects of chitosan and tio2 nanoparticles on the antibacterial property and ability to self healing of cracks and retrieve mechanical characteristics of dental composites |
| topic | Dental composites Chitosan and TiO2 nanoparticles Self-healing Cytotoxicity |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024037654 |
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