BSE can propagate in sheep co-infected or pre-infected with scrapie

BSE can propagate in sheep co-infected or pre-infected with scrapie

Abstract To understand the possible role of mixed-prion infections in disease presentation, the current study reports the co-infection of sheep with bovine spongiform encephalopathy (BSE) and scrapie. The bovine BSE agent was inoculated subcutaneously into sheep with ARQ/ARQ or VRQ/ARQ PRNP genotype...

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Bibliographic Details
Main Authors: Angela Chong, James D. Foster, Wilfred Goldmann, Lorenzo Gonzalez, Martin Jeffrey, Matthew J. O’Connor, Keith Bishop, Ben C. Maddison, E. Fiona Houston, Kevin C. Gough, Nora Hunter
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91397-8

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