Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters
(1) Background: Ocular exposure to intense light or long-time exposure to low-intensity short-wavelength lights may cause eye injury. Excessive levels of blue light induce photochemical damage to the retinal pigment and degeneration of photoreceptors of the outer segments. Currently, people spend a...
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| Format: | Article |
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MDPI AG
2021-11-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/10/11/3248 |
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| author | Celia Sanchez-Ramos Cristina Bonnin-Arias Vanesa Blázquez-Sánchez Victoria Aguirre-Vilacoro Teresa Cobo Olivia García-Suarez María Jesús Perez-Carrasco Cristina Alvarez-Peregrina José A. Vega |
| author_facet | Celia Sanchez-Ramos Cristina Bonnin-Arias Vanesa Blázquez-Sánchez Victoria Aguirre-Vilacoro Teresa Cobo Olivia García-Suarez María Jesús Perez-Carrasco Cristina Alvarez-Peregrina José A. Vega |
| author_sort | Celia Sanchez-Ramos |
| collection | DOAJ |
| description | (1) Background: Ocular exposure to intense light or long-time exposure to low-intensity short-wavelength lights may cause eye injury. Excessive levels of blue light induce photochemical damage to the retinal pigment and degeneration of photoreceptors of the outer segments. Currently, people spend a lot of time watching LED screens that emit high proportions of blue light. This study aims to assess the effects of light emitted by LED tablet screens on pigmented rat retinas with and without optical filters. (2) Methods: Commercially available tablets were used for exposure experiments on three groups of rats. One was exposed to tablet screens, the other was exposed to the tablet screens with a selective filter and the other was a control group. Structure, gene expression (including life/death, extracellular matrix degradation, growth factors, and oxidative stress related genes), and immunohistochemistry in the retina were compared among groups. (3) Results: There was a reduction of the thickness of the external nuclear layer and changes in the genes involved in cell survival and death, extracellular matrix turnover, growth factors, inflammation, and oxidative stress, leading decrease in cell density and retinal damage in the first group. Modulation of gene changes was observed when the LED light of screens was modified with an optical filter. (4) Conclusions: The use of short-wavelength selective filters on the screens contribute to reduce LED light-induced damage in the rat retina. |
| first_indexed | 2024-03-10T05:36:24Z |
| format | Article |
| id | doaj.art-838e447565e04a1483a906bb1a8fb2bf |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-10T05:36:24Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-838e447565e04a1483a906bb1a8fb2bf2023-11-22T22:53:27ZengMDPI AGCells2073-44092021-11-011011324810.3390/cells10113248Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption FiltersCelia Sanchez-Ramos0Cristina Bonnin-Arias1Vanesa Blázquez-Sánchez2Victoria Aguirre-Vilacoro3Teresa Cobo4Olivia García-Suarez5María Jesús Perez-Carrasco6Cristina Alvarez-Peregrina7José A. Vega8Grupo de Neuro-Computación y Neuro-Robótica, Facultad de Óptica y Optometría, Universidad Complutense de Madrid, 28037 Madrid, SpainGrupo de Neuro-Computación y Neuro-Robótica, Facultad de Óptica y Optometría, Universidad Complutense de Madrid, 28037 Madrid, SpainGrupo de Neuro-Computación y Neuro-Robótica, Facultad de Óptica y Optometría, Universidad Complutense de Madrid, 28037 Madrid, SpainGrupo de Neuro-Computación y Neuro-Robótica, Facultad de Óptica y Optometría, Universidad Complutense de Madrid, 28037 Madrid, SpainDepartamento de Cirugía y Especialidades Médico-Quirúrgicas, Universidad de Oviedo, 33006 Oviedo, SpainGrupo SINPOS, Departamento de Morfología y Biología Celular, Universidad de Oviedo, 33006 Oviedo, SpainDepartamento de Óptica II: Optometría y Visión, Facultad de Óptica y Optometría, Universidad Complutense de Madrid, 28037 Madrid, SpainFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Madrid, SpainGrupo SINPOS, Departamento de Morfología y Biología Celular, Universidad de Oviedo, 33006 Oviedo, Spain(1) Background: Ocular exposure to intense light or long-time exposure to low-intensity short-wavelength lights may cause eye injury. Excessive levels of blue light induce photochemical damage to the retinal pigment and degeneration of photoreceptors of the outer segments. Currently, people spend a lot of time watching LED screens that emit high proportions of blue light. This study aims to assess the effects of light emitted by LED tablet screens on pigmented rat retinas with and without optical filters. (2) Methods: Commercially available tablets were used for exposure experiments on three groups of rats. One was exposed to tablet screens, the other was exposed to the tablet screens with a selective filter and the other was a control group. Structure, gene expression (including life/death, extracellular matrix degradation, growth factors, and oxidative stress related genes), and immunohistochemistry in the retina were compared among groups. (3) Results: There was a reduction of the thickness of the external nuclear layer and changes in the genes involved in cell survival and death, extracellular matrix turnover, growth factors, inflammation, and oxidative stress, leading decrease in cell density and retinal damage in the first group. Modulation of gene changes was observed when the LED light of screens was modified with an optical filter. (4) Conclusions: The use of short-wavelength selective filters on the screens contribute to reduce LED light-induced damage in the rat retina.https://www.mdpi.com/2073-4409/10/11/3248retinal light injuryLED screenoptical filterretinal protection |
| spellingShingle | Celia Sanchez-Ramos Cristina Bonnin-Arias Vanesa Blázquez-Sánchez Victoria Aguirre-Vilacoro Teresa Cobo Olivia García-Suarez María Jesús Perez-Carrasco Cristina Alvarez-Peregrina José A. Vega Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters Cells retinal light injury LED screen optical filter retinal protection |
| title | Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters |
| title_full | Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters |
| title_fullStr | Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters |
| title_full_unstemmed | Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters |
| title_short | Retinal Protection from LED-Backlit Screen Lights by Short Wavelength Absorption Filters |
| title_sort | retinal protection from led backlit screen lights by short wavelength absorption filters |
| topic | retinal light injury LED screen optical filter retinal protection |
| url | https://www.mdpi.com/2073-4409/10/11/3248 |
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