MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY
This work is aimed at the determination of the level of molecules of intercellular adhesion of sICAM-1 and sVCAM-1 in the persons exposed to mercury. All the examined persons (88 males of 31-62) were divided into three groups: the persons with the diagnosis of chronic mercury intoxication in the pos...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2013-05-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/1560 |
| _version_ | 1797237555501989888 |
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| author | O. V. Popkova I. V. Kudaeva L. B. Masnavieva |
| author_facet | O. V. Popkova I. V. Kudaeva L. B. Masnavieva |
| author_sort | O. V. Popkova |
| collection | DOAJ |
| description | This work is aimed at the determination of the level of molecules of intercellular adhesion of sICAM-1 and sVCAM-1 in the persons exposed to mercury. All the examined persons (88 males of 31-62) were divided into three groups: the persons with the diagnosis of chronic mercury intoxication in the postponed postcontact period (1st group); the persons with the first revealed diagnosis (2nd group); the persons without professional disease working under harmful conditions for more than 5 years. Determination of the molecules was conducted using immune-enzymatic analysis method. The levels of sICAM-1 didn't differ in the 1st and 2nd groups and came to 466,2 and 430,2 ng/ml respectively, the level of sICAM-1 in the 3rd group was 219,1 ng/ml. The sVCAM-1 concentration was 337,8,126,8 and 327,4 ng/ml in the 1st, 2nd and 3rd group respectively. Increasing sVCAM-1 levels in the workers with long-term work period indicate the activation of endothelial vessel. Increased levels of sICAM-1 in patients with cardiovascular disease are related to the pathogenesis of cardiovascular disease or chronic mercury intoxication. |
| first_indexed | 2024-03-08T12:20:58Z |
| format | Article |
| id | doaj.art-8391d77e84494a90943de3441b00b9b5 |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:21:37Z |
| publishDate | 2013-05-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-8391d77e84494a90943de3441b00b9b52024-03-28T07:49:10ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962013-05-0103(1)30331506MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURYO. V. Popkova0I. V. Kudaeva1L. B. Masnavieva2Eastern Siberian Scientific Center of Human Ecology SB RAMSEastern Siberian Scientific Center of Human Ecology SB RAMSEastern Siberian Scientific Center of Human Ecology SB RAMSThis work is aimed at the determination of the level of molecules of intercellular adhesion of sICAM-1 and sVCAM-1 in the persons exposed to mercury. All the examined persons (88 males of 31-62) were divided into three groups: the persons with the diagnosis of chronic mercury intoxication in the postponed postcontact period (1st group); the persons with the first revealed diagnosis (2nd group); the persons without professional disease working under harmful conditions for more than 5 years. Determination of the molecules was conducted using immune-enzymatic analysis method. The levels of sICAM-1 didn't differ in the 1st and 2nd groups and came to 466,2 and 430,2 ng/ml respectively, the level of sICAM-1 in the 3rd group was 219,1 ng/ml. The sVCAM-1 concentration was 337,8,126,8 and 327,4 ng/ml in the 1st, 2nd and 3rd group respectively. Increasing sVCAM-1 levels in the workers with long-term work period indicate the activation of endothelial vessel. Increased levels of sICAM-1 in patients with cardiovascular disease are related to the pathogenesis of cardiovascular disease or chronic mercury intoxication.https://www.actabiomedica.ru/jour/article/view/1560sicam-1svcam-1chronic exposure to mercurychronic mercury intoxicationendothelial dysfunctioninflammationmolecules of intercellular adhesionsicam-1svcam-1 |
| spellingShingle | O. V. Popkova I. V. Kudaeva L. B. Masnavieva MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY Acta Biomedica Scientifica sicam-1 svcam-1 chronic exposure to mercury chronic mercury intoxication endothelial dysfunction inflammation molecules of intercellular adhesion sicam-1 svcam-1 |
| title | MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY |
| title_full | MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY |
| title_fullStr | MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY |
| title_full_unstemmed | MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY |
| title_short | MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY |
| title_sort | molecules of intercellular adhesion in blood sera of persons exposed to mercury |
| topic | sicam-1 svcam-1 chronic exposure to mercury chronic mercury intoxication endothelial dysfunction inflammation molecules of intercellular adhesion sicam-1 svcam-1 |
| url | https://www.actabiomedica.ru/jour/article/view/1560 |
| work_keys_str_mv | AT ovpopkova moleculesofintercellularadhesioninbloodseraofpersonsexposedtomercury AT ivkudaeva moleculesofintercellularadhesioninbloodseraofpersonsexposedtomercury AT lbmasnavieva moleculesofintercellularadhesioninbloodseraofpersonsexposedtomercury |