Arrhythmia as a cardiac manifestation in MELAS syndrome
A 44-year-old female with a diagnosis of mitochondrial myopathy, encephalopathy and stroke-like episodes (MELAS) syndrome had progressive left ventricular hypertrophy (LVH) on echocardiogram. A Holter monitor demonstrated episodes of non-sustained atrial tachycardia, a finding not been previously de...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2015-09-01
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| Series: | Molecular Genetics and Metabolism Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214426915300094 |
| _version_ | 1828524047228469248 |
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| author | Tamara Thomas William J. Craigen Ryan Moore Richard Czosek John L. Jefferies |
| author_facet | Tamara Thomas William J. Craigen Ryan Moore Richard Czosek John L. Jefferies |
| author_sort | Tamara Thomas |
| collection | DOAJ |
| description | A 44-year-old female with a diagnosis of mitochondrial myopathy, encephalopathy and stroke-like episodes (MELAS) syndrome had progressive left ventricular hypertrophy (LVH) on echocardiogram. A Holter monitor demonstrated episodes of non-sustained atrial tachycardia, a finding not been previously described in this population. This unique case of MELAS syndrome demonstrates the known associated cardiac manifestation of LVH and the new finding of atrial tachycardia which may represent the potential for subclinical arrhythmia in this population. |
| first_indexed | 2024-12-11T20:39:09Z |
| format | Article |
| id | doaj.art-8392671632ab4860b3731612c2391c98 |
| institution | Directory Open Access Journal |
| issn | 2214-4269 |
| language | English |
| last_indexed | 2024-12-11T20:39:09Z |
| publishDate | 2015-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Molecular Genetics and Metabolism Reports |
| spelling | doaj.art-8392671632ab4860b3731612c2391c982022-12-22T00:51:34ZengElsevierMolecular Genetics and Metabolism Reports2214-42692015-09-014C91010.1016/j.ymgmr.2015.05.002Arrhythmia as a cardiac manifestation in MELAS syndromeTamara Thomas0William J. Craigen1Ryan Moore2Richard Czosek3John L. Jefferies4Arkansas Children's Hospital, Little Rock, AR, United StatesTexas Children's Genetics Clinic, Texas Children's Hospital, Houston, TX, United StatesThe Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United StatesThe Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United StatesThe Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United StatesA 44-year-old female with a diagnosis of mitochondrial myopathy, encephalopathy and stroke-like episodes (MELAS) syndrome had progressive left ventricular hypertrophy (LVH) on echocardiogram. A Holter monitor demonstrated episodes of non-sustained atrial tachycardia, a finding not been previously described in this population. This unique case of MELAS syndrome demonstrates the known associated cardiac manifestation of LVH and the new finding of atrial tachycardia which may represent the potential for subclinical arrhythmia in this population.http://www.sciencedirect.com/science/article/pii/S2214426915300094ArrhythmiaHeart failureMELASMitochondria |
| spellingShingle | Tamara Thomas William J. Craigen Ryan Moore Richard Czosek John L. Jefferies Arrhythmia as a cardiac manifestation in MELAS syndrome Molecular Genetics and Metabolism Reports Arrhythmia Heart failure MELAS Mitochondria |
| title | Arrhythmia as a cardiac manifestation in MELAS syndrome |
| title_full | Arrhythmia as a cardiac manifestation in MELAS syndrome |
| title_fullStr | Arrhythmia as a cardiac manifestation in MELAS syndrome |
| title_full_unstemmed | Arrhythmia as a cardiac manifestation in MELAS syndrome |
| title_short | Arrhythmia as a cardiac manifestation in MELAS syndrome |
| title_sort | arrhythmia as a cardiac manifestation in melas syndrome |
| topic | Arrhythmia Heart failure MELAS Mitochondria |
| url | http://www.sciencedirect.com/science/article/pii/S2214426915300094 |
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