Investigation of the Exometabolomic Profiles of Rat Islets of Langerhans Cultured in Microfluidic Biochip

Investigation of the Exometabolomic Profiles of Rat Islets of Langerhans Cultured in Microfluidic Biochip

Diabetes mellitus (DM) is a complex disease with high prevalence of comorbidity and mortality. DM is predicted to reach more than 700 million people by 2045. In recent years, several advanced in vitro models and analytical tools were developed to investigate the pancreatic tissue response to patholo...

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Bibliographic Details
Main Authors: Amal Essaouiba, Rachid Jellali, Françoise Gilard, Bertrand Gakière, Teru Okitsu, Cécile Legallais, Yasuyuki Sakai, Eric Leclerc
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Metabolites
Subjects:
microfluidic culture
biochip
islets of Langerhans
exometabolome
diabetes
Online Access:https://www.mdpi.com/2218-1989/12/12/1270

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