KSHV-encoded LANA protects the cellular replication machinery from hypoxia induced degradation.

KSHV-encoded LANA protects the cellular replication machinery from hypoxia induced degradation.

Kaposi's sarcoma associated herpesvirus (KSHV), like all herpesviruses maintains lifelong persistence with its host genome in latently infected cells with only a small fraction of cells showing signatures of productive lytic replication. Modulation of cellular signaling pathways by KSHV-encoded...

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Bibliographic Details
Main Authors: Rajnish Kumar Singh, Zachary L Lamplugh, Fengchao Lang, Yan Yuan, Paul Lieberman, Jianxin You, Erle S Robertson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008025

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