Clinical characteristics and etiology of children with bronchiolitis before and during the COVID-19 pandemic in Suzhou, China
ObjectiveWe sought to compare the clinical characteristics and etiology of children with bronchiolitis in Suzhou before the pandemic of coronavirus disease 2019 (COVID-19) with those during the pandemic.MethodsChildren who were hospitalized with bronchiolitis in the Department of Respiratory Disease...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.974769/full |
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| author | Xiaohui Jiang Xiaohui Jiang Ting Wang Ge Dai Huiming Sun Wujun Jiang Zhengrong Chen Yongdong Yan |
| author_facet | Xiaohui Jiang Xiaohui Jiang Ting Wang Ge Dai Huiming Sun Wujun Jiang Zhengrong Chen Yongdong Yan |
| author_sort | Xiaohui Jiang |
| collection | DOAJ |
| description | ObjectiveWe sought to compare the clinical characteristics and etiology of children with bronchiolitis in Suzhou before the pandemic of coronavirus disease 2019 (COVID-19) with those during the pandemic.MethodsChildren who were hospitalized with bronchiolitis in the Department of Respiratory Disease, Children's Hospital of Soochow University were retrospectively enrolled over 3 consecutive years (2019, 2020, and 2021) from February 1 to January 31. Medical records were reviewed for etiology, clinical manifestations, and laboratory examination results.ResultsThe pathogen detection rate and the positive respiratory syncytial virus (RSV) detection rate were lowest in 2020 and highest in 2021. The rate of human rhinovirus detection in 2021 was higher than that in 2019 but similar to that in 2020. The RSV-positive rate differences among the 3 years varied by age group. Regarding the monthly distribution of RSV-positive cases over the 3-year study, all age groups showed a significant increase in the number of cases during the winter of 2021, and this increase started as early as October. With regard to clinical manifestations, the proportion of children presenting with stuffy nose rhinorrhea in 2021 [73.33% (165/225)] was greater than that in 2019 [48.61% (122/251)] and 2020 [57.06% (97/170)], while the proportion of children with gastrointestinal symptoms in 2021 [11.56% (26/225)] was smaller than that in 2019 [25.50% (64/251)] but similar to that in 2020 [17.06% (29/170)].ConclusionsAfter the implementation of COVID-19 pandemic-related interventions, significantly lower pathogen detection and RSV-positive rates were observed in children with bronchiolitis in 2020. An upward trend in these rates was observed in 2021, coinciding with the relaxation of COVID-19 prevention measures. Strengthening infection control and surveillance systems is extremely important for future work. |
| first_indexed | 2024-04-11T08:07:02Z |
| format | Article |
| id | doaj.art-8397dc0059b04b4294d616004e6bb36b |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-11T08:07:02Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-8397dc0059b04b4294d616004e6bb36b2022-12-22T04:35:29ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-11-011010.3389/fped.2022.974769974769Clinical characteristics and etiology of children with bronchiolitis before and during the COVID-19 pandemic in Suzhou, ChinaXiaohui Jiang0Xiaohui Jiang1Ting Wang2Ge Dai3Huiming Sun4Wujun Jiang5Zhengrong Chen6Yongdong Yan7Department of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, ChinaDepartment of Pediatrics, Huaian Hospital of Huaian City, Huaian, ChinaDepartment of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, ChinaDepartment of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, ChinaDepartment of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, ChinaDepartment of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, ChinaDepartment of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, ChinaDepartment of Respiratory Medicine, Children’s Hospital of Soochow University, Suzhou, ChinaObjectiveWe sought to compare the clinical characteristics and etiology of children with bronchiolitis in Suzhou before the pandemic of coronavirus disease 2019 (COVID-19) with those during the pandemic.MethodsChildren who were hospitalized with bronchiolitis in the Department of Respiratory Disease, Children's Hospital of Soochow University were retrospectively enrolled over 3 consecutive years (2019, 2020, and 2021) from February 1 to January 31. Medical records were reviewed for etiology, clinical manifestations, and laboratory examination results.ResultsThe pathogen detection rate and the positive respiratory syncytial virus (RSV) detection rate were lowest in 2020 and highest in 2021. The rate of human rhinovirus detection in 2021 was higher than that in 2019 but similar to that in 2020. The RSV-positive rate differences among the 3 years varied by age group. Regarding the monthly distribution of RSV-positive cases over the 3-year study, all age groups showed a significant increase in the number of cases during the winter of 2021, and this increase started as early as October. With regard to clinical manifestations, the proportion of children presenting with stuffy nose rhinorrhea in 2021 [73.33% (165/225)] was greater than that in 2019 [48.61% (122/251)] and 2020 [57.06% (97/170)], while the proportion of children with gastrointestinal symptoms in 2021 [11.56% (26/225)] was smaller than that in 2019 [25.50% (64/251)] but similar to that in 2020 [17.06% (29/170)].ConclusionsAfter the implementation of COVID-19 pandemic-related interventions, significantly lower pathogen detection and RSV-positive rates were observed in children with bronchiolitis in 2020. An upward trend in these rates was observed in 2021, coinciding with the relaxation of COVID-19 prevention measures. Strengthening infection control and surveillance systems is extremely important for future work.https://www.frontiersin.org/articles/10.3389/fped.2022.974769/fullbronchiolitisclinical characteristicsetiologyCOVID-19 pandemicrespiratory syncytial virus |
| spellingShingle | Xiaohui Jiang Xiaohui Jiang Ting Wang Ge Dai Huiming Sun Wujun Jiang Zhengrong Chen Yongdong Yan Clinical characteristics and etiology of children with bronchiolitis before and during the COVID-19 pandemic in Suzhou, China Frontiers in Pediatrics bronchiolitis clinical characteristics etiology COVID-19 pandemic respiratory syncytial virus |
| title | Clinical characteristics and etiology of children with bronchiolitis before and during the COVID-19 pandemic in Suzhou, China |
| title_full | Clinical characteristics and etiology of children with bronchiolitis before and during the COVID-19 pandemic in Suzhou, China |
| title_fullStr | Clinical characteristics and etiology of children with bronchiolitis before and during the COVID-19 pandemic in Suzhou, China |
| title_full_unstemmed | Clinical characteristics and etiology of children with bronchiolitis before and during the COVID-19 pandemic in Suzhou, China |
| title_short | Clinical characteristics and etiology of children with bronchiolitis before and during the COVID-19 pandemic in Suzhou, China |
| title_sort | clinical characteristics and etiology of children with bronchiolitis before and during the covid 19 pandemic in suzhou china |
| topic | bronchiolitis clinical characteristics etiology COVID-19 pandemic respiratory syncytial virus |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.974769/full |
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