Latent tuberculosis in migrants travelling through the northeast regions of Mexico
Background: Latent tuberculosis infection (LTBI) affects nearly a quarter of the global population. Public health interventions aimed at interrupting tuberculosis transmission do not routinely include systematic screening of migrant populations for LTBI in Mexico, nor other high-income countries. Ho...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-12-01
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| Series: | Journal of Clinical Tuberculosis and Other Mycobacterial Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405579420300589 |
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| author | Obed Medina-Macías Philippe Stoesslé Leonardo E. Perales-Rendón Jorge E. Moreno-Cuevas Francisco González-Salazar |
| author_facet | Obed Medina-Macías Philippe Stoesslé Leonardo E. Perales-Rendón Jorge E. Moreno-Cuevas Francisco González-Salazar |
| author_sort | Obed Medina-Macías |
| collection | DOAJ |
| description | Background: Latent tuberculosis infection (LTBI) affects nearly a quarter of the global population. Public health interventions aimed at interrupting tuberculosis transmission do not routinely include systematic screening of migrant populations for LTBI in Mexico, nor other high-income countries. However, early detection and treatment of LTBI in immigrant populations from high-burden countries are recommended by the World Health Organization. Objective: The objective of this study was to determine the proportion of migrants with LTBI in shelters in northeastern Mexico. Methods: In this cross-sectional study, blood samples were obtained from 455 migrants living in shelters in northeastern Mexico during January 2017 to October 2019. LTBI was diagnosed using the QuantiFERON®-TB Gold Plus test. Results: Most of the migrants evaluated in this study were from Honduras; ∼86% were male; the average age was 29 ± 10 years. LTBI was identified in 18.4% of those from Central America. Migrants from El Salvador and Nicaragua were more likely to have LTBI than those from Honduras or Guatemala. Overweight or obese persons and older persons had a higher prevalence of LTBI. We detected no significant differences with respect to LTBI when the results were compared based on gender, education, or marital status. Conclusion: The LTBI rates amongst migrants from Central America recently screened in shelters in northeastern Mexico appears to be relatively low given recent estimates of LTBI prevalence in Mexico. |
| first_indexed | 2024-12-19T05:51:31Z |
| format | Article |
| id | doaj.art-83998ea9762b43aba62a127972d47019 |
| institution | Directory Open Access Journal |
| issn | 2405-5794 |
| language | English |
| last_indexed | 2024-12-19T05:51:31Z |
| publishDate | 2020-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Clinical Tuberculosis and Other Mycobacterial Diseases |
| spelling | doaj.art-83998ea9762b43aba62a127972d470192022-12-21T20:33:35ZengElsevierJournal of Clinical Tuberculosis and Other Mycobacterial Diseases2405-57942020-12-0121100194Latent tuberculosis in migrants travelling through the northeast regions of MexicoObed Medina-Macías0Philippe Stoesslé1Leonardo E. Perales-Rendón2Jorge E. Moreno-Cuevas3Francisco González-Salazar4División de Ciencias de La Salud, Departamento de Ciencias Básicas, Universidad de Monterrey, Monterrey, MexicoDepartamento de Ciencias Sociales, Universidad de Monterrey, Monterrey, MexicoCentro de Investigaciones Biomédicas Del Noreste, Instituto Mexicano Del Seguro Social, Monterrey, MexicoDivisión de Ciencias de La Salud, Departamento de Ciencias Básicas, Universidad de Monterrey, Monterrey, MexicoDivisión de Ciencias de La Salud, Departamento de Ciencias Básicas, Universidad de Monterrey, Monterrey, Mexico; Centro de Investigaciones Biomédicas Del Noreste, Instituto Mexicano Del Seguro Social, Monterrey, Mexico; Corresponding author at: Francisco González Salazar, 2 de abril y San Luis Potosí, Colonia Independencia, Monterrey, Nuevo León México CP: 64720, Mexico.Background: Latent tuberculosis infection (LTBI) affects nearly a quarter of the global population. Public health interventions aimed at interrupting tuberculosis transmission do not routinely include systematic screening of migrant populations for LTBI in Mexico, nor other high-income countries. However, early detection and treatment of LTBI in immigrant populations from high-burden countries are recommended by the World Health Organization. Objective: The objective of this study was to determine the proportion of migrants with LTBI in shelters in northeastern Mexico. Methods: In this cross-sectional study, blood samples were obtained from 455 migrants living in shelters in northeastern Mexico during January 2017 to October 2019. LTBI was diagnosed using the QuantiFERON®-TB Gold Plus test. Results: Most of the migrants evaluated in this study were from Honduras; ∼86% were male; the average age was 29 ± 10 years. LTBI was identified in 18.4% of those from Central America. Migrants from El Salvador and Nicaragua were more likely to have LTBI than those from Honduras or Guatemala. Overweight or obese persons and older persons had a higher prevalence of LTBI. We detected no significant differences with respect to LTBI when the results were compared based on gender, education, or marital status. Conclusion: The LTBI rates amongst migrants from Central America recently screened in shelters in northeastern Mexico appears to be relatively low given recent estimates of LTBI prevalence in Mexico.http://www.sciencedirect.com/science/article/pii/S2405579420300589TuberculosisLatent tuberculosisMigrantsInterferon-gamma release assaysEnzyme-linked immunosorbent assay |
| spellingShingle | Obed Medina-Macías Philippe Stoesslé Leonardo E. Perales-Rendón Jorge E. Moreno-Cuevas Francisco González-Salazar Latent tuberculosis in migrants travelling through the northeast regions of Mexico Journal of Clinical Tuberculosis and Other Mycobacterial Diseases Tuberculosis Latent tuberculosis Migrants Interferon-gamma release assays Enzyme-linked immunosorbent assay |
| title | Latent tuberculosis in migrants travelling through the northeast regions of Mexico |
| title_full | Latent tuberculosis in migrants travelling through the northeast regions of Mexico |
| title_fullStr | Latent tuberculosis in migrants travelling through the northeast regions of Mexico |
| title_full_unstemmed | Latent tuberculosis in migrants travelling through the northeast regions of Mexico |
| title_short | Latent tuberculosis in migrants travelling through the northeast regions of Mexico |
| title_sort | latent tuberculosis in migrants travelling through the northeast regions of mexico |
| topic | Tuberculosis Latent tuberculosis Migrants Interferon-gamma release assays Enzyme-linked immunosorbent assay |
| url | http://www.sciencedirect.com/science/article/pii/S2405579420300589 |
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