Receptor-induced thiolate couples Env activation to retrovirus fusion and infection.

According to current models of retrovirus infection, receptor binding to the surface subunit (SU) of the envelope glycoprotein (Env) triggers a conformational change in the transmembrane subunit (TM) that mediates virus fusion to cell membranes. To understand how this occurs, we investigated the rol...

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Bibliographic Details
Main Authors: Jason G Smith, James M Cunningham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18260686/?tool=EBI