Upfront Surgery versus Neoadjuvant Perioperative Chemotherapy for Resectable Colorectal Liver Metastases: A Machine-Learning Decision Tree to Identify the Best Potential Candidates under a Parenchyma-Sparing Policy

Upfront Surgery versus Neoadjuvant Perioperative Chemotherapy for Resectable Colorectal Liver Metastases: A Machine-Learning Decision Tree to Identify the Best Potential Candidates under a Parenchyma-Sparing Policy

Addressing patients to neoadjuvant systemic chemotherapy followed by surgery rather than surgical resection upfront is controversial in the case of resectable colorectal –liver metastases (CLM). The aim of this study was to develop a machine-learning model to identify the best potential candidates f...

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Bibliographic Details
Main Authors: Simone Famularo, Flavio Milana, Matteo Cimino, Eloisa Franchi, Mario Giuffrida, Guido Costa, Fabio Procopio, Matteo Donadon, Guido Torzilli
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
liver surgery
colorectal liver metastases
upfront surgery
neoadjuvant chemotherapy
machine-learning
Online Access:https://www.mdpi.com/2072-6694/15/3/613

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