Influence of Vitamin D on the Vasoactive Effect of Estradiol in a Rat Model of Polycystic Ovary Syndrome

Influence of Vitamin D on the Vasoactive Effect of Estradiol in a Rat Model of Polycystic Ovary Syndrome

We examined the vasoactive effect of estradiol in a rat model of early PCOS and the influence of vitamin D deficiency (VDD). We created a model of chronic hyperandrogenism and VDD in adolescent female Wistar rats (N = 46) with four experimental groups: vitamin D supplemented (T-D+), VDD (T-D-), hype...

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Main Authors: Róbert Tarszabó, Bálint Bányai, Éva Ruisanchez, Borbála Péterffy, Ágnes Korsós-Novák, Krisztina Lajtai, Réka Eszter Sziva, Dóra Gerszi, Ádám Hosszú, Rita Benkő, Zoltán Benyó, Eszter Mária Horváth, Gabriella Masszi, Szabolcs Várbíró
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
polycystic ovary syndrome
vitamin D deficiency
rat model
estradiol relaxation
testosterone treatment
Online Access:https://www.mdpi.com/1422-0067/22/17/9404

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