Effects of COVID-19 vaccine type on Guillain-Barré syndrome: Two cases and a literature review
Guillain-Barré syndrome (GBS) is a rare but severe complication of COVID-19 vaccination. We report two cases of GBS following vaccination with the adenovirus vector vaccine ChAdOx1 nCoV-19 (Vaxzevria, AstraZeneca) and review the relevant literature. Relevant studies published between December 2020 a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-01-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2023.2171231 |
| _version_ | 1797673116042788864 |
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| author | Hsin-Yu Lee Wan-Ching Lien |
| author_facet | Hsin-Yu Lee Wan-Ching Lien |
| author_sort | Hsin-Yu Lee |
| collection | DOAJ |
| description | Guillain-Barré syndrome (GBS) is a rare but severe complication of COVID-19 vaccination. We report two cases of GBS following vaccination with the adenovirus vector vaccine ChAdOx1 nCoV-19 (Vaxzevria, AstraZeneca) and review the relevant literature. Relevant studies published between December 2020 and May 2022 including 881 patients with GBS were reviewed. GBS incidence and the need for mechanical ventilation were reported at a higher level among patients receiving Vaxzevria (n = 400). However, incidence cannot be accurately estimated from case reports. Thus, the true GBS rates following COVID-19 vaccination should be determined by population-based data. |
| first_indexed | 2024-03-11T21:39:51Z |
| format | Article |
| id | doaj.art-83a9239b09454c20a25a52ab509d8883 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T21:39:51Z |
| publishDate | 2023-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-83a9239b09454c20a25a52ab509d88832023-09-26T13:25:48ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2023-01-0119110.1080/21645515.2023.21712312171231Effects of COVID-19 vaccine type on Guillain-Barré syndrome: Two cases and a literature reviewHsin-Yu Lee0Wan-Ching Lien1National Taiwan University HospitalNational Taiwan University HospitalGuillain-Barré syndrome (GBS) is a rare but severe complication of COVID-19 vaccination. We report two cases of GBS following vaccination with the adenovirus vector vaccine ChAdOx1 nCoV-19 (Vaxzevria, AstraZeneca) and review the relevant literature. Relevant studies published between December 2020 and May 2022 including 881 patients with GBS were reviewed. GBS incidence and the need for mechanical ventilation were reported at a higher level among patients receiving Vaxzevria (n = 400). However, incidence cannot be accurately estimated from case reports. Thus, the true GBS rates following COVID-19 vaccination should be determined by population-based data.http://dx.doi.org/10.1080/21645515.2023.2171231covid-19 vaccineguillain-barré syndrome |
| spellingShingle | Hsin-Yu Lee Wan-Ching Lien Effects of COVID-19 vaccine type on Guillain-Barré syndrome: Two cases and a literature review Human Vaccines & Immunotherapeutics covid-19 vaccine guillain-barré syndrome |
| title | Effects of COVID-19 vaccine type on Guillain-Barré syndrome: Two cases and a literature review |
| title_full | Effects of COVID-19 vaccine type on Guillain-Barré syndrome: Two cases and a literature review |
| title_fullStr | Effects of COVID-19 vaccine type on Guillain-Barré syndrome: Two cases and a literature review |
| title_full_unstemmed | Effects of COVID-19 vaccine type on Guillain-Barré syndrome: Two cases and a literature review |
| title_short | Effects of COVID-19 vaccine type on Guillain-Barré syndrome: Two cases and a literature review |
| title_sort | effects of covid 19 vaccine type on guillain barre syndrome two cases and a literature review |
| topic | covid-19 vaccine guillain-barré syndrome |
| url | http://dx.doi.org/10.1080/21645515.2023.2171231 |
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