Dexmedetomidine versus magnesium sulfate as adjunct to general anesthesia in patients undergoing video-assisted thoracoscopy
Abstract Background This study was designed to evaluate the effects of infusion of magnesium sulfate compared to dexmedetomidine on the postoperative analgesic consumption and pain control in patients scheduled for video-assisted thoracoscopic surgeries (VATS). The intraoperative hemodynamics, anest...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-01-01
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| Series: | Ain Shams Journal of Anesthesiology |
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| Online Access: | https://doi.org/10.1186/s42077-021-00209-8 |
| _version_ | 1798016342359539712 |
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| author | Mohammed Abdelsalam Menshawi Hany Magdy Fahim |
| author_facet | Mohammed Abdelsalam Menshawi Hany Magdy Fahim |
| author_sort | Mohammed Abdelsalam Menshawi |
| collection | DOAJ |
| description | Abstract Background This study was designed to evaluate the effects of infusion of magnesium sulfate compared to dexmedetomidine on the postoperative analgesic consumption and pain control in patients scheduled for video-assisted thoracoscopic surgeries (VATS). The intraoperative hemodynamics, anesthesia requirements, and recovery profile were also evaluated. Results The mean arterial pressure (MAP) and heart rate (HR) recordings were significantly lower in group D than in groups C and M. The MAP recordings were significantly lower in group M than in group C with no significant difference as regards the HR recordings between both groups. Intraoperative sevoflurane and fentanyl requirements were significantly lower in groups D and M than in group C and in group D than in group M. The atracurium consumption was significantly lower in group M than in groups C and D. The time to reach modified Aldrete score ≥ 9 was significantly longer in groups D and M than in group C and in group D than in group M. Postoperative Ramsay sedation scores were significantly higher in groups D and M than in group C throughout the PACU stay and in group D than in group M in the 1st h postoperatively. The VAS score recordings were significantly lower in groups D and M than in group C and in group D than in group M except at 24-h postoperative recordings. The postoperative nalbuphine and ketorolac requirements were significantly lower in groups D and M than in group C and in group D than in group M. Conclusions During VATS, patients who received dexmedetomidine had better hemodynamic stability, less intraoperative anesthetic consumption with better quality of postoperative analgesia, and less postoperative analgesic consumption but longer postoperative anesthesia recovery and higher postoperative sedation scores compared with magnesium sulfate. |
| first_indexed | 2024-04-11T15:49:13Z |
| format | Article |
| id | doaj.art-83ad093c312645819edd90459cb3af73 |
| institution | Directory Open Access Journal |
| issn | 2090-925X |
| language | English |
| last_indexed | 2024-04-11T15:49:13Z |
| publishDate | 2022-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Ain Shams Journal of Anesthesiology |
| spelling | doaj.art-83ad093c312645819edd90459cb3af732022-12-22T04:15:26ZengSpringerOpenAin Shams Journal of Anesthesiology2090-925X2022-01-0114111010.1186/s42077-021-00209-8Dexmedetomidine versus magnesium sulfate as adjunct to general anesthesia in patients undergoing video-assisted thoracoscopyMohammed Abdelsalam Menshawi0Hany Magdy Fahim1Faculty of Medicine, Ain Shams UniversityFaculty of Medicine, Ain Shams UniversityAbstract Background This study was designed to evaluate the effects of infusion of magnesium sulfate compared to dexmedetomidine on the postoperative analgesic consumption and pain control in patients scheduled for video-assisted thoracoscopic surgeries (VATS). The intraoperative hemodynamics, anesthesia requirements, and recovery profile were also evaluated. Results The mean arterial pressure (MAP) and heart rate (HR) recordings were significantly lower in group D than in groups C and M. The MAP recordings were significantly lower in group M than in group C with no significant difference as regards the HR recordings between both groups. Intraoperative sevoflurane and fentanyl requirements were significantly lower in groups D and M than in group C and in group D than in group M. The atracurium consumption was significantly lower in group M than in groups C and D. The time to reach modified Aldrete score ≥ 9 was significantly longer in groups D and M than in group C and in group D than in group M. Postoperative Ramsay sedation scores were significantly higher in groups D and M than in group C throughout the PACU stay and in group D than in group M in the 1st h postoperatively. The VAS score recordings were significantly lower in groups D and M than in group C and in group D than in group M except at 24-h postoperative recordings. The postoperative nalbuphine and ketorolac requirements were significantly lower in groups D and M than in group C and in group D than in group M. Conclusions During VATS, patients who received dexmedetomidine had better hemodynamic stability, less intraoperative anesthetic consumption with better quality of postoperative analgesia, and less postoperative analgesic consumption but longer postoperative anesthesia recovery and higher postoperative sedation scores compared with magnesium sulfate.https://doi.org/10.1186/s42077-021-00209-8Video-assisted thoracoscopyDexmedetomidineMagnesium sulfate |
| spellingShingle | Mohammed Abdelsalam Menshawi Hany Magdy Fahim Dexmedetomidine versus magnesium sulfate as adjunct to general anesthesia in patients undergoing video-assisted thoracoscopy Ain Shams Journal of Anesthesiology Video-assisted thoracoscopy Dexmedetomidine Magnesium sulfate |
| title | Dexmedetomidine versus magnesium sulfate as adjunct to general anesthesia in patients undergoing video-assisted thoracoscopy |
| title_full | Dexmedetomidine versus magnesium sulfate as adjunct to general anesthesia in patients undergoing video-assisted thoracoscopy |
| title_fullStr | Dexmedetomidine versus magnesium sulfate as adjunct to general anesthesia in patients undergoing video-assisted thoracoscopy |
| title_full_unstemmed | Dexmedetomidine versus magnesium sulfate as adjunct to general anesthesia in patients undergoing video-assisted thoracoscopy |
| title_short | Dexmedetomidine versus magnesium sulfate as adjunct to general anesthesia in patients undergoing video-assisted thoracoscopy |
| title_sort | dexmedetomidine versus magnesium sulfate as adjunct to general anesthesia in patients undergoing video assisted thoracoscopy |
| topic | Video-assisted thoracoscopy Dexmedetomidine Magnesium sulfate |
| url | https://doi.org/10.1186/s42077-021-00209-8 |
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