Evaluation of Antimicrobial Activity of Probiotic Lactobacillus Strains against Growth and Urease Activity of Proteus spp.
Background: Nowadays, the use of probiotic bacteria for the prevention and treatment of urinary tract infections is growing. Lactobacillus, as probiotic bacterial genus, is well known for its benefits for the human health. Methods: The effects of partially purified antimicrobial compounds (...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2017-10-01
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| Series: | Journal of Medical Bacteriology |
| Subjects: | |
| Online Access: | https://jmb.tums.ac.ir/index.php/jmb/article/view/335 |
| _version_ | 1818059156789133312 |
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| author | Leila Goudarzi Rouha Kasra Kermanshahi Zahra Moosavi-Nejad Mohammad Mehdi Soltan Dalla |
| author_facet | Leila Goudarzi Rouha Kasra Kermanshahi Zahra Moosavi-Nejad Mohammad Mehdi Soltan Dalla |
| author_sort | Leila Goudarzi |
| collection | DOAJ |
| description | Background: Nowadays, the use of probiotic bacteria for the prevention and treatment of urinary tract infections is growing. Lactobacillus, as probiotic bacterial genus, is well known for its benefits for the human health.
Methods: The effects of partially purified antimicrobial compounds (bacteriocins and biosurfactants) of Lactobacillus strains was assessed and their capacity to in vitro inhibit growth and urease production of various strains of Proteus spp, was studied. Inhibition of the urease production of Proteus spp. at sub-MIC levels was screened using spectrophotometry method.
Results: Results revealed that semi-purified bacteriocins of L. acidophilus and L. plantarum showed a greater inhibitory activity on the bacterial urease, compared to biosurfactants of L. rhamnosus, L. casei and L. fermentum (P < 0.05).
Conclusion: It can be concluded that bacteriocins may affect Proteus pathogenesis by inhibition of the bacterial urease activity and therefore eliminate the stone formation by these bacteria. |
| first_indexed | 2024-12-10T13:12:03Z |
| format | Article |
| id | doaj.art-83ad7b53cccd40e98049519d403ba842 |
| institution | Directory Open Access Journal |
| issn | 2251-8649 2322-2581 |
| language | English |
| last_indexed | 2024-12-10T13:12:03Z |
| publishDate | 2017-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Medical Bacteriology |
| spelling | doaj.art-83ad7b53cccd40e98049519d403ba8422022-12-22T01:47:38ZengTehran University of Medical SciencesJournal of Medical Bacteriology2251-86492322-25812017-10-0163-4291Evaluation of Antimicrobial Activity of Probiotic Lactobacillus Strains against Growth and Urease Activity of Proteus spp.Leila Goudarzi0Rouha Kasra Kermanshahi1Zahra Moosavi-Nejad2Mohammad Mehdi Soltan Dalla3Department of Microbiology, Faculty of Sciences, Alzahra University, Tehran, Iran. Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, Iran.Department of Microbiology, Faculty of Sciences, Alzahra University, Tehran, Iran.Department of Biology, Faculty of Basic Sciences, Alzahra University, Tehran, Iran.Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Division of Food Microbiology, Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran..Background: Nowadays, the use of probiotic bacteria for the prevention and treatment of urinary tract infections is growing. Lactobacillus, as probiotic bacterial genus, is well known for its benefits for the human health. Methods: The effects of partially purified antimicrobial compounds (bacteriocins and biosurfactants) of Lactobacillus strains was assessed and their capacity to in vitro inhibit growth and urease production of various strains of Proteus spp, was studied. Inhibition of the urease production of Proteus spp. at sub-MIC levels was screened using spectrophotometry method. Results: Results revealed that semi-purified bacteriocins of L. acidophilus and L. plantarum showed a greater inhibitory activity on the bacterial urease, compared to biosurfactants of L. rhamnosus, L. casei and L. fermentum (P < 0.05). Conclusion: It can be concluded that bacteriocins may affect Proteus pathogenesis by inhibition of the bacterial urease activity and therefore eliminate the stone formation by these bacteria.https://jmb.tums.ac.ir/index.php/jmb/article/view/335Antimicrobial activityLactobacillus sppProbiotic bacteriaProteus sppUreas |
| spellingShingle | Leila Goudarzi Rouha Kasra Kermanshahi Zahra Moosavi-Nejad Mohammad Mehdi Soltan Dalla Evaluation of Antimicrobial Activity of Probiotic Lactobacillus Strains against Growth and Urease Activity of Proteus spp. Journal of Medical Bacteriology Antimicrobial activity Lactobacillus spp Probiotic bacteria Proteus spp Ureas |
| title | Evaluation of Antimicrobial Activity of Probiotic Lactobacillus Strains against Growth and Urease Activity of Proteus spp. |
| title_full | Evaluation of Antimicrobial Activity of Probiotic Lactobacillus Strains against Growth and Urease Activity of Proteus spp. |
| title_fullStr | Evaluation of Antimicrobial Activity of Probiotic Lactobacillus Strains against Growth and Urease Activity of Proteus spp. |
| title_full_unstemmed | Evaluation of Antimicrobial Activity of Probiotic Lactobacillus Strains against Growth and Urease Activity of Proteus spp. |
| title_short | Evaluation of Antimicrobial Activity of Probiotic Lactobacillus Strains against Growth and Urease Activity of Proteus spp. |
| title_sort | evaluation of antimicrobial activity of probiotic lactobacillus strains against growth and urease activity of proteus spp |
| topic | Antimicrobial activity Lactobacillus spp Probiotic bacteria Proteus spp Ureas |
| url | https://jmb.tums.ac.ir/index.php/jmb/article/view/335 |
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