A meta-analysis of fMRI studies of language comprehension in children
The neural representation of language comprehension has been examined in several meta-analyses of fMRI studies with human adults. To complement this work from a developmental perspective, we conducted a meta-analysis of fMRI studies of auditory language comprehension in human children. Our analysis...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-07-01
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| Series: | NeuroImage |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S105381192030344X |
| _version_ | 1818962929431609344 |
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| author | Alexander Enge Angela D. Friederici Michael A. Skeide |
| author_facet | Alexander Enge Angela D. Friederici Michael A. Skeide |
| author_sort | Alexander Enge |
| collection | DOAJ |
| description | The neural representation of language comprehension has been examined in several meta-analyses of fMRI studies with human adults. To complement this work from a developmental perspective, we conducted a meta-analysis of fMRI studies of auditory language comprehension in human children. Our analysis included 27 independent experiments involving n = 625 children (49% girls) with a mean age of 8.9 years. Activation likelihood estimation and seed-based effect size mapping revealed activation peaks in the pars triangularis of the left inferior frontal gyrus and bilateral superior and middle temporal gyri. In contrast to this distribution of activation in children, previous work in adults found activation peaks in the pars opercularis of the left inferior frontal gyrus and more left-lateralized temporal activation peaks. Accordingly, brain responses during language comprehension may shift from bilateral temporal and left pars triangularis peaks in childhood to left temporal and pars opercularis peaks in adulthood. This shift could be related to the gradually increasing sensitivity of the developing brain to syntactic information. |
| first_indexed | 2024-12-20T12:37:08Z |
| format | Article |
| id | doaj.art-83add957943c44dd897e9f023aea95e8 |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-12-20T12:37:08Z |
| publishDate | 2020-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-83add957943c44dd897e9f023aea95e82022-12-21T19:40:34ZengElsevierNeuroImage1095-95722020-07-01215116858A meta-analysis of fMRI studies of language comprehension in childrenAlexander Enge0Angela D. Friederici1Michael A. Skeide2Department of Neuropsychology, Max Planck Institute for Human Cognitive and Brain Sciences, 04103, Leipzig, Germany; Department of Psychology, Humboldt-Universität zu Berlin, 12489, Berlin, GermanyDepartment of Neuropsychology, Max Planck Institute for Human Cognitive and Brain Sciences, 04103, Leipzig, GermanyDepartment of Neuropsychology, Max Planck Institute for Human Cognitive and Brain Sciences, 04103, Leipzig, Germany; Corresponding author. Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstrasse 1A, 04103, Leipzig, Germany.The neural representation of language comprehension has been examined in several meta-analyses of fMRI studies with human adults. To complement this work from a developmental perspective, we conducted a meta-analysis of fMRI studies of auditory language comprehension in human children. Our analysis included 27 independent experiments involving n = 625 children (49% girls) with a mean age of 8.9 years. Activation likelihood estimation and seed-based effect size mapping revealed activation peaks in the pars triangularis of the left inferior frontal gyrus and bilateral superior and middle temporal gyri. In contrast to this distribution of activation in children, previous work in adults found activation peaks in the pars opercularis of the left inferior frontal gyrus and more left-lateralized temporal activation peaks. Accordingly, brain responses during language comprehension may shift from bilateral temporal and left pars triangularis peaks in childhood to left temporal and pars opercularis peaks in adulthood. This shift could be related to the gradually increasing sensitivity of the developing brain to syntactic information.http://www.sciencedirect.com/science/article/pii/S105381192030344X |
| spellingShingle | Alexander Enge Angela D. Friederici Michael A. Skeide A meta-analysis of fMRI studies of language comprehension in children NeuroImage |
| title | A meta-analysis of fMRI studies of language comprehension in children |
| title_full | A meta-analysis of fMRI studies of language comprehension in children |
| title_fullStr | A meta-analysis of fMRI studies of language comprehension in children |
| title_full_unstemmed | A meta-analysis of fMRI studies of language comprehension in children |
| title_short | A meta-analysis of fMRI studies of language comprehension in children |
| title_sort | meta analysis of fmri studies of language comprehension in children |
| url | http://www.sciencedirect.com/science/article/pii/S105381192030344X |
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