Dysbiosis of human tumor microbiome and aberrant residence of Actinomyces in tumor-associated fibroblasts in young-onset colorectal cancer

Dysbiosis of human tumor microbiome and aberrant residence of Actinomyces in tumor-associated fibroblasts in young-onset colorectal cancer

Colorectal cancer (CRC) is the third most common form of cancer, and the incidence of sporadic young-onset colorectal cancer (yCRC) has been increasing. Microbiota residing in the tumor microenvironment are emerging tumor components. The colonic microbiome differs between patients with CRC and healt...

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Bibliographic Details
Main Authors: Zhuoqing Xu, Zeping Lv, Fangqian Chen, Yuchen Zhang, Zifeng Xu, Jianting Huo, Wangyi Liu, Suyue Yu, Abudumaimaitijiang Tuersun, Jingkun Zhao, Yaping Zong, Xiaonan Shen, Wenqing Feng, Aiguo Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
young-onset colorectal cancer
microbiome
Actinomyces
TLR2
cancer-associated fibroblasts (CAFs)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1008975/full

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