Long-term surgical outcomes of primary congenital glaucoma in China
OBJECTIVE: To evaluate the long-term outcomes of three surgical procedures for the treatment of primary congenital glaucoma (PCG). INTRODUCTION: PCG is one of the main causes of blindness in children. There is a paucity of contemporary data on PCG in China. METHODS: A retrospective study of 48 patie...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier España
2009-06-01
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| Series: | Clinics |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322009000600009 |
| _version_ | 1818115430405898240 |
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| author | Xiulan Zhang Shaolin Du Qian Fan Shouxiong Peng Minbin Yu Jian Ge |
| author_facet | Xiulan Zhang Shaolin Du Qian Fan Shouxiong Peng Minbin Yu Jian Ge |
| author_sort | Xiulan Zhang |
| collection | DOAJ |
| description | OBJECTIVE: To evaluate the long-term outcomes of three surgical procedures for the treatment of primary congenital glaucoma (PCG). INTRODUCTION: PCG is one of the main causes of blindness in children. There is a paucity of contemporary data on PCG in China. METHODS: A retrospective study of 48 patients (81 eyes) with PCG who underwent primary trabeculectomy, trabeculotomy, or combined trabeculotomy and trabeculectomy (CTT). RESULTS: All patients were less than 4 years (yrs) of age, with a mean age of 2.08 ± 1.23 yrs. The mean duration of follow-up was 5.49 ± 3.09 yrs. The difference in success rates among the three surgical procedures at 1, 3, 6 and 9 yrs was not statistically significant (p = 0.492). However, in patients with over 4 yrs of follow-up, Kaplan-Meier survival analysis revealed that the success rates of trabeculectomy and CTT declined more slowly than that of trabeculotomy. Among the patients, 66.22% acquired good vision (VA > 0.4), 17.57% acquired fair vision (VA = 0.1 - 0.3), and 16.22% acquired poor vision (VA < 0.1). The patients with good vision were mostly in the successful surgery group. Myopia was more prevalent postoperatively (p = 0.009). Reductions in the cup-disc ratio and corneal diameter were only seen in the successful surgery group (p = 0.000). In addition, the successful surgery group contained more patients that complied with a regular follow-up routine (p = 0.002). DISCUSSION: Our cases were all primary surgeries. Primary trabeculectomy was performed in many cases because no treatment was sought until an advanced stage of disease had been reached. CONCLUSIONS: In contrast to most reports, in the present study, trabeculectomy and CTT achieved higher long-term success rates than trabeculotomy. The patients with successful surgical results had better vision. Compliance with a routine of regular follow-up may increase the chances of a successful surgical outcome. |
| first_indexed | 2024-12-11T04:06:30Z |
| format | Article |
| id | doaj.art-83b44745aaec4e43a156cc75de0d57ff |
| institution | Directory Open Access Journal |
| issn | 1807-5932 1980-5322 |
| language | English |
| last_indexed | 2024-12-11T04:06:30Z |
| publishDate | 2009-06-01 |
| publisher | Elsevier España |
| record_format | Article |
| series | Clinics |
| spelling | doaj.art-83b44745aaec4e43a156cc75de0d57ff2022-12-22T01:21:30ZengElsevier EspañaClinics1807-59321980-53222009-06-0164654355110.1590/S1807-59322009000600009Long-term surgical outcomes of primary congenital glaucoma in ChinaXiulan ZhangShaolin DuQian FanShouxiong PengMinbin YuJian GeOBJECTIVE: To evaluate the long-term outcomes of three surgical procedures for the treatment of primary congenital glaucoma (PCG). INTRODUCTION: PCG is one of the main causes of blindness in children. There is a paucity of contemporary data on PCG in China. METHODS: A retrospective study of 48 patients (81 eyes) with PCG who underwent primary trabeculectomy, trabeculotomy, or combined trabeculotomy and trabeculectomy (CTT). RESULTS: All patients were less than 4 years (yrs) of age, with a mean age of 2.08 ± 1.23 yrs. The mean duration of follow-up was 5.49 ± 3.09 yrs. The difference in success rates among the three surgical procedures at 1, 3, 6 and 9 yrs was not statistically significant (p = 0.492). However, in patients with over 4 yrs of follow-up, Kaplan-Meier survival analysis revealed that the success rates of trabeculectomy and CTT declined more slowly than that of trabeculotomy. Among the patients, 66.22% acquired good vision (VA > 0.4), 17.57% acquired fair vision (VA = 0.1 - 0.3), and 16.22% acquired poor vision (VA < 0.1). The patients with good vision were mostly in the successful surgery group. Myopia was more prevalent postoperatively (p = 0.009). Reductions in the cup-disc ratio and corneal diameter were only seen in the successful surgery group (p = 0.000). In addition, the successful surgery group contained more patients that complied with a regular follow-up routine (p = 0.002). DISCUSSION: Our cases were all primary surgeries. Primary trabeculectomy was performed in many cases because no treatment was sought until an advanced stage of disease had been reached. CONCLUSIONS: In contrast to most reports, in the present study, trabeculectomy and CTT achieved higher long-term success rates than trabeculotomy. The patients with successful surgical results had better vision. Compliance with a routine of regular follow-up may increase the chances of a successful surgical outcome.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322009000600009Primary congenital glaucoma (PCG)TrabeculectomyTrabeculotomyCombined trabeculotomy and trabeculectomy (CTT)China |
| spellingShingle | Xiulan Zhang Shaolin Du Qian Fan Shouxiong Peng Minbin Yu Jian Ge Long-term surgical outcomes of primary congenital glaucoma in China Clinics Primary congenital glaucoma (PCG) Trabeculectomy Trabeculotomy Combined trabeculotomy and trabeculectomy (CTT) China |
| title | Long-term surgical outcomes of primary congenital glaucoma in China |
| title_full | Long-term surgical outcomes of primary congenital glaucoma in China |
| title_fullStr | Long-term surgical outcomes of primary congenital glaucoma in China |
| title_full_unstemmed | Long-term surgical outcomes of primary congenital glaucoma in China |
| title_short | Long-term surgical outcomes of primary congenital glaucoma in China |
| title_sort | long term surgical outcomes of primary congenital glaucoma in china |
| topic | Primary congenital glaucoma (PCG) Trabeculectomy Trabeculotomy Combined trabeculotomy and trabeculectomy (CTT) China |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322009000600009 |
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