Synthesis and Antiproliferative Activity of New Cyclodiprenyl Phenols against Select Cancer Cell Lines

Synthesis and Antiproliferative Activity of New Cyclodiprenyl Phenols against Select Cancer Cell Lines

Six new cyclodiprenyl phenols were synthesized by direct coupling of perillyl alcohol and the appropriate phenol. Their structures were established by IR, HRMS and mainly NMR. Three human cancer cell lines—breast (MCF-7), prostate (PC-3) and colon (HT-29)—were used in antiprolife...

Full description

Bibliographic Details
Main Authors: Bastián Said, Iván Montenegro, Manuel Valenzuela, Yusser Olguín, Nelson Caro, Enrique Werner, Patricio Godoy, Joan Villena, Alejandro Madrid
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Molecules
Subjects:
perillyl alcohol
synthesis
cyclodiprenyl phenols
antiproliferative agents
Online Access:http://www.mdpi.com/1420-3049/23/9/2323

Similar Items

Similar Items