Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort studyResearch in Context
Summary: Background: China has the highest prevalence of spontaneous intracerebral hemorrhage (sICH) worldwide. To date, no national-level report has revealed sICH surgical performance. We aimed to investigate the current status and short-term outcomes of patients who underwent surgical treatment f...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-10-01
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| Series: | The Lancet Regional Health. Western Pacific |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666606523001888 |
| _version_ | 1797753897373138944 |
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| author | Ye Li Hongyi Yang Lei Cao Penghu Wei Yuhong Liu Tao Wang Xue Wang Xuesong Bai Liqun Jiao Hongqi Zhang Yongzhi Shan Longde Wang Guoguang Zhao |
| author_facet | Ye Li Hongyi Yang Lei Cao Penghu Wei Yuhong Liu Tao Wang Xue Wang Xuesong Bai Liqun Jiao Hongqi Zhang Yongzhi Shan Longde Wang Guoguang Zhao |
| author_sort | Ye Li |
| collection | DOAJ |
| description | Summary: Background: China has the highest prevalence of spontaneous intracerebral hemorrhage (sICH) worldwide. To date, no national-level report has revealed sICH surgical performance. We aimed to investigate the current status and short-term outcomes of patients who underwent surgical treatment for sICH between 2019 and 2021. Methods: Data from 7451 patients undergoing sICH surgical treatment in China between 2019 and 2021, including demographic information, disease severity, surgical treatments for sICH, complications, and follow-up information, were retrieved from the Bigdata Observatory Platform for Stroke of China. Propensity score matching (PSM) was applied to balance the baseline characteristics. The surgical treatment performance on 3-month mortality and functional outcome were then explored by regression analysis. The influence of stroke center level and region on surgical performance was then explored. Findings: The numbers of sICH patients undergoing open craniotomy (OC), cranial puncture (CP), decompressive craniectomy (DC) and endoscopic evacuation (EE) were 2404 (32.3%), 3030 (40.7%), 1700 (22.8%) and 317 (4.3%), respectively. The 3-month mortality rate was 20.2%. Among the surviving patients, the 3-month poor functional prognosis (mRS 3–5) rate was 46.5%. After PSM, regression analysis showed that DC was associated with a higher mortality risk (OR = 1.31, 95% CI 1.06–1.61) than OC. CP was associated with a lower risk of poor mRS scores than OC (OR = 0.84, 95% CI 0.70–1.01), especially in stroke prevention centers and specific regions. Interpretation: Outcome improvements in Chinese sICH patients undergoing surgical treatment are worth expecting. Inconsistent surgical performance, especially functional outcome, affected by inhomogeneity of the hospital should be addressed. Funding: This work was supported by the Beijing Hospitals Authority Youth Programme (QML20230804), the National Natural Science Foundation of China (81701796, 82030037, 81871009), Capital Health Research and Development of Special Fund (2020-2Z-2019), Science and Technology Innovation 2030-Major Project (2021ZD0201801), and the Translational and Application Project of Brain-inspired and Network Neuroscience on Brain Disorders (11000022T000000444685). |
| first_indexed | 2024-03-12T17:25:35Z |
| format | Article |
| id | doaj.art-83b66f49a02748d286b1834c8e46c677 |
| institution | Directory Open Access Journal |
| issn | 2666-6065 |
| language | English |
| last_indexed | 2024-03-12T17:25:35Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | The Lancet Regional Health. Western Pacific |
| spelling | doaj.art-83b66f49a02748d286b1834c8e46c6772023-08-05T05:17:55ZengElsevierThe Lancet Regional Health. Western Pacific2666-60652023-10-0139100870Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort studyResearch in ContextYe Li0Hongyi Yang1Lei Cao2Penghu Wei3Yuhong Liu4Tao Wang5Xue Wang6Xuesong Bai7Liqun Jiao8Hongqi Zhang9Yongzhi Shan10Longde Wang11Guoguang Zhao12Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, ChinaGeneral Office of the Stroke Prevention Project Committee, National Health Commission of the People's Republic of China, Beijing, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, China; National Center for Neurological Disorders, Beijing 100053, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing 100069, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, ChinaMedical Library of Xuanwu Hospital, Xuanwu Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, ChinaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, China; Corresponding author. Xuanwu Hospital, Capital Medical University, No. 45 Changchun St., Xicheng District, Beijing 100053, China.General Office of the Stroke Prevention Project Committee, National Health Commission of the People's Republic of China, Beijing, China; School of Public Health, Peking University, Beijing, China; Corresponding author. No. 118, Guang’anmen Inner Street, Beijing 100053, PR China.Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing 100053, China; National Center for Neurological Disorders, Beijing 100053, China; Beijing Municipal Geriatric Medical Research Center, Beijing 100053, China; Corresponding author. Xuanwu Hospital, Capital Medical University, No. 45 Changchun St., Xicheng District, Beijing 100053, China.Summary: Background: China has the highest prevalence of spontaneous intracerebral hemorrhage (sICH) worldwide. To date, no national-level report has revealed sICH surgical performance. We aimed to investigate the current status and short-term outcomes of patients who underwent surgical treatment for sICH between 2019 and 2021. Methods: Data from 7451 patients undergoing sICH surgical treatment in China between 2019 and 2021, including demographic information, disease severity, surgical treatments for sICH, complications, and follow-up information, were retrieved from the Bigdata Observatory Platform for Stroke of China. Propensity score matching (PSM) was applied to balance the baseline characteristics. The surgical treatment performance on 3-month mortality and functional outcome were then explored by regression analysis. The influence of stroke center level and region on surgical performance was then explored. Findings: The numbers of sICH patients undergoing open craniotomy (OC), cranial puncture (CP), decompressive craniectomy (DC) and endoscopic evacuation (EE) were 2404 (32.3%), 3030 (40.7%), 1700 (22.8%) and 317 (4.3%), respectively. The 3-month mortality rate was 20.2%. Among the surviving patients, the 3-month poor functional prognosis (mRS 3–5) rate was 46.5%. After PSM, regression analysis showed that DC was associated with a higher mortality risk (OR = 1.31, 95% CI 1.06–1.61) than OC. CP was associated with a lower risk of poor mRS scores than OC (OR = 0.84, 95% CI 0.70–1.01), especially in stroke prevention centers and specific regions. Interpretation: Outcome improvements in Chinese sICH patients undergoing surgical treatment are worth expecting. Inconsistent surgical performance, especially functional outcome, affected by inhomogeneity of the hospital should be addressed. Funding: This work was supported by the Beijing Hospitals Authority Youth Programme (QML20230804), the National Natural Science Foundation of China (81701796, 82030037, 81871009), Capital Health Research and Development of Special Fund (2020-2Z-2019), Science and Technology Innovation 2030-Major Project (2021ZD0201801), and the Translational and Application Project of Brain-inspired and Network Neuroscience on Brain Disorders (11000022T000000444685).http://www.sciencedirect.com/science/article/pii/S2666606523001888Intracerebral hemorrhageShort-term outcomesOpen craniotomyCranial punctureDecompressive craniectomyEndoscopic evacuation |
| spellingShingle | Ye Li Hongyi Yang Lei Cao Penghu Wei Yuhong Liu Tao Wang Xue Wang Xuesong Bai Liqun Jiao Hongqi Zhang Yongzhi Shan Longde Wang Guoguang Zhao Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort studyResearch in Context The Lancet Regional Health. Western Pacific Intracerebral hemorrhage Short-term outcomes Open craniotomy Cranial puncture Decompressive craniectomy Endoscopic evacuation |
| title | Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort studyResearch in Context |
| title_full | Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort studyResearch in Context |
| title_fullStr | Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort studyResearch in Context |
| title_full_unstemmed | Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort studyResearch in Context |
| title_short | Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort studyResearch in Context |
| title_sort | short term surgical outcomes of spontaneous intracerebral hemorrhage in china from 2019 to 2021 a retrospective cohort studyresearch in context |
| topic | Intracerebral hemorrhage Short-term outcomes Open craniotomy Cranial puncture Decompressive craniectomy Endoscopic evacuation |
| url | http://www.sciencedirect.com/science/article/pii/S2666606523001888 |
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