Cases of Yolk sac tumor associated with gynecological malignant tumor
Abstract Background Yolk sac tumour (YST) is the second most common ovarian germ cell tumour and usually presents in children and young women. However, tumours rarely occur as malignant gynaecological tumours with YST components. Case presentation We present one case of endometrioid carcinoma and cl...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | BMC Women's Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12905-023-02495-w |
| _version_ | 1797789572682219520 |
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| author | Shengchao Wang Kelie Chen Qin Chen Shuai Huang Weiguo Lu |
| author_facet | Shengchao Wang Kelie Chen Qin Chen Shuai Huang Weiguo Lu |
| author_sort | Shengchao Wang |
| collection | DOAJ |
| description | Abstract Background Yolk sac tumour (YST) is the second most common ovarian germ cell tumour and usually presents in children and young women. However, tumours rarely occur as malignant gynaecological tumours with YST components. Case presentation We present one case of endometrioid carcinoma and clear cell carcinoma with YST components and two other cases of YSTs associated with high-grade serous carcinoma of the ovary in females. After surgery and adjuvant chemotherapy, the patient with endometrioid carcinoma had progressive disease and died 20 months later, and the other two were still alive at the last follow-up. Conclusions To our knowledge, these mixed neoplasm associations are unusual, and these cases illustrate the diagnosis and prognosis of YST associated with malignant gynaecological tumours, emphasizing early recognition and aggressive treatment. |
| first_indexed | 2024-03-13T01:52:35Z |
| format | Article |
| id | doaj.art-83c0ce5c509a4379887fb9cb5ee2ed68 |
| institution | Directory Open Access Journal |
| issn | 1472-6874 |
| language | English |
| last_indexed | 2024-03-13T01:52:35Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Women's Health |
| spelling | doaj.art-83c0ce5c509a4379887fb9cb5ee2ed682023-07-02T11:26:00ZengBMCBMC Women's Health1472-68742023-06-012311610.1186/s12905-023-02495-wCases of Yolk sac tumor associated with gynecological malignant tumorShengchao Wang0Kelie Chen1Qin Chen2Shuai Huang3Weiguo Lu4Department of Gynecological Oncology, Women’s Hospital, Zhejiang University School of MedicineDepartment of Gynecological Oncology, Women’s Hospital, Zhejiang University School of MedicineDepartment of Gynecological Oncology, Women’s Hospital, Zhejiang University School of MedicineDepartment of Gynecological Oncology, Women’s Hospital, Zhejiang University School of MedicineDepartment of Gynecological Oncology, Women’s Hospital, Zhejiang University School of MedicineAbstract Background Yolk sac tumour (YST) is the second most common ovarian germ cell tumour and usually presents in children and young women. However, tumours rarely occur as malignant gynaecological tumours with YST components. Case presentation We present one case of endometrioid carcinoma and clear cell carcinoma with YST components and two other cases of YSTs associated with high-grade serous carcinoma of the ovary in females. After surgery and adjuvant chemotherapy, the patient with endometrioid carcinoma had progressive disease and died 20 months later, and the other two were still alive at the last follow-up. Conclusions To our knowledge, these mixed neoplasm associations are unusual, and these cases illustrate the diagnosis and prognosis of YST associated with malignant gynaecological tumours, emphasizing early recognition and aggressive treatment.https://doi.org/10.1186/s12905-023-02495-wYolk sac tumour (YST)Malignant gynaecological tumoursTreatmentChemotherapyPrognosis |
| spellingShingle | Shengchao Wang Kelie Chen Qin Chen Shuai Huang Weiguo Lu Cases of Yolk sac tumor associated with gynecological malignant tumor BMC Women's Health Yolk sac tumour (YST) Malignant gynaecological tumours Treatment Chemotherapy Prognosis |
| title | Cases of Yolk sac tumor associated with gynecological malignant tumor |
| title_full | Cases of Yolk sac tumor associated with gynecological malignant tumor |
| title_fullStr | Cases of Yolk sac tumor associated with gynecological malignant tumor |
| title_full_unstemmed | Cases of Yolk sac tumor associated with gynecological malignant tumor |
| title_short | Cases of Yolk sac tumor associated with gynecological malignant tumor |
| title_sort | cases of yolk sac tumor associated with gynecological malignant tumor |
| topic | Yolk sac tumour (YST) Malignant gynaecological tumours Treatment Chemotherapy Prognosis |
| url | https://doi.org/10.1186/s12905-023-02495-w |
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