The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus

The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus

Summary: Complement-dependent microglia pruning of excitatory synapses has been widely reported in physiological and pathological conditions, with few reports concerning pruning of inhibitory synapses or direct regulation of synaptic transmission by complement components. Here, we report that loss o...

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Bibliographic Details
Main Authors: Lang Wen, Xiaoli Yang, Zujun Wu, Shumei Fu, Yaxi Zhan, Zuolong Chen, Danlei Bi, Yong Shen
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723003601

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