Formation of Extracellular Traps - the Effective Mechanism of Organism Protection from Pathogen
Summarized and analyzed are modern literature data on capability of cells (neutrophils, eosinophils and labrocytes) realizing the mechanisms of innate immunity, to form extracellular traps that capture and kill pathogens by secretion of DNA and antibacterial granules content into extracellular space...
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| Format: | Article |
| Language: | Russian |
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Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
2012-04-01
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| Series: | Проблемы особо опасных инфекций |
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| Online Access: | https://journal.microbe.ru/jour/article/view/800 |
| Summary: | Summarized and analyzed are modern literature data on capability of cells (neutrophils, eosinophils and labrocytes) realizing the mechanisms of innate immunity, to form extracellular traps that capture and kill pathogens by secretion of DNA and antibacterial granules content into extracellular space. The efficiency of capture and bacterial clearance is higher in extracellular traps than that in phagocytosis. The mechanism of extracellular bactericidal activity is supposed to play an important role in protection of organism from bacteria which are resistant to phagocytosis by leukocytes. |
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| ISSN: | 0370-1069 2658-719X |