Identification of the Anti-sickling Activity of Anogeissus leiocarpus and In Silico Investigation of Some of Its Phytochemicals

Identification of the Anti-sickling Activity of Anogeissus leiocarpus and In Silico Investigation of Some of Its Phytochemicals

Abstract Background: The anti-sickling activity of Anogeissus leiocarpus, a plant used for managing sickle cell disease (SCD), has been previously proven. Objectives: This study investigated the anti-sickling mechanism of A. leiocarpus by probing its effects on Gardos channel (KCNN4), erythropoie...

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Bibliographic Details
Main Authors: Taiwo O. Elufioye, Babatunde M. Williams, Mojisola C. Cyril-Olutayo
Format: Article
Language:English
Published: Hamadan University of Medical Sciences 2020-06-01
Series:Avicenna Journal of Medical Biochemistry
Subjects:
sickle cell anaemia
anogeissus leiocarpus
gardos channel
erythropoiesis
mechanism of action
Online Access:http://ajmb.umsha.ac.ir/PDF/ajmb-8-1.pdf

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