Normative reference values and regression equations to predict the 6-minute walk distance in the Asian adult population aged 21–80 years
Summary at a glance: The 6-min walk test (6MWT) is a widely used field walking test. This study reports the normative reference values (NRV) of distance walked during 6MWT (6MWD) in healthy Singaporeans (aged 21–80) and updates the 6MWD reference equations. This information may facilitate the interp...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2022-12-01
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| Series: | Hong Kong Physiotherapy Journal |
| Subjects: | |
| Online Access: | https://www.worldscientific.com/doi/10.1142/S1013702522500111 |
| _version_ | 1797996358241615872 |
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| author | Meredith T. Yeung Melissa Y. Chan Katherin S. Huang Tian Jie Chen Cyprian P. Chia Meihiko M. Fong Cherilyn S. Ho Derek T. Koh Mitchell J. Neo Mark Tan |
| author_facet | Meredith T. Yeung Melissa Y. Chan Katherin S. Huang Tian Jie Chen Cyprian P. Chia Meihiko M. Fong Cherilyn S. Ho Derek T. Koh Mitchell J. Neo Mark Tan |
| author_sort | Meredith T. Yeung |
| collection | DOAJ |
| description | Summary at a glance: The 6-min walk test (6MWT) is a widely used field walking test. This study reports the normative reference values (NRV) of distance walked during 6MWT (6MWD) in healthy Singaporeans (aged 21–80) and updates the 6MWD reference equations. This information may facilitate the interpretation of the 6MWD in clinical populations. Ethics approval: The Singapore Institute of Technology-Institutional Review Board (SIT-IRB Project Number: 2019099) approved this study to be carried out from June 2019 to January 2021. All participants gave written informed consent before data collection began. Background: The six-minute walk test (6MWT) is a widely adopted submaximal field-walking test to evaluate functional exercise capacity. This validated test is a reliable, safe, inexpensive, and straightforward assessment tool commonly used as an outcome measure, using the distance walked (6MWD) as the primary outcome. An earlier study has established the normative reference values (NRV) and equation in healthy Singaporeans — however, the small sample size and narrow age range curb adequate representation of the adult population profile. Objectives: This study aims to update the NRV and reference equations to predict the distance walked during 6MWT (6MWD) for healthy Singaporeans aged 21–80. Methods: This cross-sectional study recruited community-dwelling healthy subjects aged 21–80 via convenience sampling. Each subject completed two trials of 6MWT according to the standard protocol. Primary outcome measures included 6MWD, pre-and post-test heart rate (HR), oxygen saturation, and blood pressure (BP). Results: 172 healthy Singaporeans ([Formula: see text], [Formula: see text]) participated. The overall mean 6MWD was [Formula: see text] metres. The age-stratified mean 6MWD ranged from [Formula: see text] metres (aged 21–39) to [Formula: see text] metres (aged 60–80). Age, gender, and percentage maximum HR predicted (%PredHRmax) were the most significant variables ([Formula: see text]). 6MWD reference [Formula: see text] [Formula: see text] (HR reserve, bpm) [Formula: see text] (weight, kg), [Formula: see text]. Applying equations from other studies to the Singaporean population resulted in an overestimation of the 6MWD. Conclusion: This study updated the NRV and reference equations of 6MWD for healthy Singaporeans aged between 21–80 years. This update revises the local benchmarks of 6MWD in Singapore, a widely adopted outcome measure. |
| first_indexed | 2024-04-11T10:16:19Z |
| format | Article |
| id | doaj.art-83c608cfe4a7429c9248c2c32f10c903 |
| institution | Directory Open Access Journal |
| issn | 1013-7025 1876-441X |
| language | English |
| last_indexed | 2024-04-11T10:16:19Z |
| publishDate | 2022-12-01 |
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| series | Hong Kong Physiotherapy Journal |
| spelling | doaj.art-83c608cfe4a7429c9248c2c32f10c9032022-12-22T04:29:58ZengWorld Scientific PublishingHong Kong Physiotherapy Journal1013-70251876-441X2022-12-01420211112410.1142/S1013702522500111Normative reference values and regression equations to predict the 6-minute walk distance in the Asian adult population aged 21–80 yearsMeredith T. Yeung0Melissa Y. Chan1Katherin S. Huang2Tian Jie Chen3Cyprian P. Chia4Meihiko M. Fong5Cherilyn S. Ho6Derek T. Koh7Mitchell J. Neo8Mark Tan9Health and Social Sciences Cluster, Singapore Institute of Technology, SingaporeHealth and Social Sciences Cluster, Singapore Institute of Technology, SingaporeHealth and Social Sciences Cluster, Singapore Institute of Technology, SingaporeHealth and Social Sciences Cluster, Singapore Institute of Technology, SingaporeHealth and Social Sciences Cluster, Singapore Institute of Technology, SingaporeHealth and Social Sciences Cluster, Singapore Institute of Technology, SingaporeHealth and Social Sciences Cluster, Singapore Institute of Technology, SingaporeHealth and Social Sciences Cluster, Singapore Institute of Technology, SingaporeHealth and Social Sciences Cluster, Singapore Institute of Technology, SingaporeHealth and Social Sciences Cluster, Singapore Institute of Technology, SingaporeSummary at a glance: The 6-min walk test (6MWT) is a widely used field walking test. This study reports the normative reference values (NRV) of distance walked during 6MWT (6MWD) in healthy Singaporeans (aged 21–80) and updates the 6MWD reference equations. This information may facilitate the interpretation of the 6MWD in clinical populations. Ethics approval: The Singapore Institute of Technology-Institutional Review Board (SIT-IRB Project Number: 2019099) approved this study to be carried out from June 2019 to January 2021. All participants gave written informed consent before data collection began. Background: The six-minute walk test (6MWT) is a widely adopted submaximal field-walking test to evaluate functional exercise capacity. This validated test is a reliable, safe, inexpensive, and straightforward assessment tool commonly used as an outcome measure, using the distance walked (6MWD) as the primary outcome. An earlier study has established the normative reference values (NRV) and equation in healthy Singaporeans — however, the small sample size and narrow age range curb adequate representation of the adult population profile. Objectives: This study aims to update the NRV and reference equations to predict the distance walked during 6MWT (6MWD) for healthy Singaporeans aged 21–80. Methods: This cross-sectional study recruited community-dwelling healthy subjects aged 21–80 via convenience sampling. Each subject completed two trials of 6MWT according to the standard protocol. Primary outcome measures included 6MWD, pre-and post-test heart rate (HR), oxygen saturation, and blood pressure (BP). Results: 172 healthy Singaporeans ([Formula: see text], [Formula: see text]) participated. The overall mean 6MWD was [Formula: see text] metres. The age-stratified mean 6MWD ranged from [Formula: see text] metres (aged 21–39) to [Formula: see text] metres (aged 60–80). Age, gender, and percentage maximum HR predicted (%PredHRmax) were the most significant variables ([Formula: see text]). 6MWD reference [Formula: see text] [Formula: see text] (HR reserve, bpm) [Formula: see text] (weight, kg), [Formula: see text]. Applying equations from other studies to the Singaporean population resulted in an overestimation of the 6MWD. Conclusion: This study updated the NRV and reference equations of 6MWD for healthy Singaporeans aged between 21–80 years. This update revises the local benchmarks of 6MWD in Singapore, a widely adopted outcome measure.https://www.worldscientific.com/doi/10.1142/S10137025225001116-Minute walk testexercise testexercise capacityoutcome measuresreference values and equations |
| spellingShingle | Meredith T. Yeung Melissa Y. Chan Katherin S. Huang Tian Jie Chen Cyprian P. Chia Meihiko M. Fong Cherilyn S. Ho Derek T. Koh Mitchell J. Neo Mark Tan Normative reference values and regression equations to predict the 6-minute walk distance in the Asian adult population aged 21–80 years Hong Kong Physiotherapy Journal 6-Minute walk test exercise test exercise capacity outcome measures reference values and equations |
| title | Normative reference values and regression equations to predict the 6-minute walk distance in the Asian adult population aged 21–80 years |
| title_full | Normative reference values and regression equations to predict the 6-minute walk distance in the Asian adult population aged 21–80 years |
| title_fullStr | Normative reference values and regression equations to predict the 6-minute walk distance in the Asian adult population aged 21–80 years |
| title_full_unstemmed | Normative reference values and regression equations to predict the 6-minute walk distance in the Asian adult population aged 21–80 years |
| title_short | Normative reference values and regression equations to predict the 6-minute walk distance in the Asian adult population aged 21–80 years |
| title_sort | normative reference values and regression equations to predict the 6 minute walk distance in the asian adult population aged 21 80 years |
| topic | 6-Minute walk test exercise test exercise capacity outcome measures reference values and equations |
| url | https://www.worldscientific.com/doi/10.1142/S1013702522500111 |
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