Manganese ferrite nanocubes as an MRI contrast agent

Facile synthesis of superparamagnetic, highly crystalline, manganese ferrite nanocubes (MnNCs) is reported. X-ray diffraction depicts single-phase face-centred cubic spinel and the electron microscopy represents the nearly monodispersed cube-like nanostructure with the size ranging from 18 to 20 nm....

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Main Authors: M Ravichandran, S Velumani
Format: Article
Language:English
Published: IOP Publishing 2020-01-01
Series:Materials Research Express
Subjects:
Online Access:https://doi.org/10.1088/2053-1591/ab66a4
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author M Ravichandran
S Velumani
author_facet M Ravichandran
S Velumani
author_sort M Ravichandran
collection DOAJ
description Facile synthesis of superparamagnetic, highly crystalline, manganese ferrite nanocubes (MnNCs) is reported. X-ray diffraction depicts single-phase face-centred cubic spinel and the electron microscopy represents the nearly monodispersed cube-like nanostructure with the size ranging from 18 to 20 nm. Vibrating sample magnetometer shows magnetization field-dependent curves at 300 K exhibiting the superparamagnetic behaviour of NCs with negligible remanence. Furthermore, the biocompatibility of NCs was proved by MTT assay. These unique characteristics make this NCs as a contrast agent ideally suited for T _2 -weighted MR imaging. This novel method of synthesizing NCs proves to be very attractive for various biomedical applications because of their outstanding stability and biocompatibility.
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spelling doaj.art-83c80422c7924c59a39b4fc295f844f52023-08-09T15:26:30ZengIOP PublishingMaterials Research Express2053-15912020-01-017101610710.1088/2053-1591/ab66a4Manganese ferrite nanocubes as an MRI contrast agentM Ravichandran0https://orcid.org/0000-0002-2934-0717S Velumani1Centro de Física Aplicada y Tecnología Avanzada, Universidad Nacional Autónoma de México , Boulevard Juriquilla, Querétaro, Qro., México; Program on Nanoscience and Nanotechnology, CINVESTAV-IPN, Avenida IPN 6508, San Pedro Zacatenco, D F, MexicoProgram on Nanoscience and Nanotechnology, CINVESTAV-IPN, Avenida IPN 6508, San Pedro Zacatenco, D F, Mexico; Department of Electrical Engineering (SEES), CINVESTAV-IPN, Avenida IPN 6508, San Pedro Zacatenco, D F MexicoFacile synthesis of superparamagnetic, highly crystalline, manganese ferrite nanocubes (MnNCs) is reported. X-ray diffraction depicts single-phase face-centred cubic spinel and the electron microscopy represents the nearly monodispersed cube-like nanostructure with the size ranging from 18 to 20 nm. Vibrating sample magnetometer shows magnetization field-dependent curves at 300 K exhibiting the superparamagnetic behaviour of NCs with negligible remanence. Furthermore, the biocompatibility of NCs was proved by MTT assay. These unique characteristics make this NCs as a contrast agent ideally suited for T _2 -weighted MR imaging. This novel method of synthesizing NCs proves to be very attractive for various biomedical applications because of their outstanding stability and biocompatibility.https://doi.org/10.1088/2053-1591/ab66a4manganese ferritenanocubeMRIbiocompatiblesuperparamagnetic
spellingShingle M Ravichandran
S Velumani
Manganese ferrite nanocubes as an MRI contrast agent
Materials Research Express
manganese ferrite
nanocube
MRI
biocompatible
superparamagnetic
title Manganese ferrite nanocubes as an MRI contrast agent
title_full Manganese ferrite nanocubes as an MRI contrast agent
title_fullStr Manganese ferrite nanocubes as an MRI contrast agent
title_full_unstemmed Manganese ferrite nanocubes as an MRI contrast agent
title_short Manganese ferrite nanocubes as an MRI contrast agent
title_sort manganese ferrite nanocubes as an mri contrast agent
topic manganese ferrite
nanocube
MRI
biocompatible
superparamagnetic
url https://doi.org/10.1088/2053-1591/ab66a4
work_keys_str_mv AT mravichandran manganeseferritenanocubesasanmricontrastagent
AT svelumani manganeseferritenanocubesasanmricontrastagent