Manganese ferrite nanocubes as an MRI contrast agent
Facile synthesis of superparamagnetic, highly crystalline, manganese ferrite nanocubes (MnNCs) is reported. X-ray diffraction depicts single-phase face-centred cubic spinel and the electron microscopy represents the nearly monodispersed cube-like nanostructure with the size ranging from 18 to 20 nm....
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
IOP Publishing
2020-01-01
|
Series: | Materials Research Express |
Subjects: | |
Online Access: | https://doi.org/10.1088/2053-1591/ab66a4 |
_version_ | 1797747022105673728 |
---|---|
author | M Ravichandran S Velumani |
author_facet | M Ravichandran S Velumani |
author_sort | M Ravichandran |
collection | DOAJ |
description | Facile synthesis of superparamagnetic, highly crystalline, manganese ferrite nanocubes (MnNCs) is reported. X-ray diffraction depicts single-phase face-centred cubic spinel and the electron microscopy represents the nearly monodispersed cube-like nanostructure with the size ranging from 18 to 20 nm. Vibrating sample magnetometer shows magnetization field-dependent curves at 300 K exhibiting the superparamagnetic behaviour of NCs with negligible remanence. Furthermore, the biocompatibility of NCs was proved by MTT assay. These unique characteristics make this NCs as a contrast agent ideally suited for T _2 -weighted MR imaging. This novel method of synthesizing NCs proves to be very attractive for various biomedical applications because of their outstanding stability and biocompatibility. |
first_indexed | 2024-03-12T15:46:07Z |
format | Article |
id | doaj.art-83c80422c7924c59a39b4fc295f844f5 |
institution | Directory Open Access Journal |
issn | 2053-1591 |
language | English |
last_indexed | 2024-03-12T15:46:07Z |
publishDate | 2020-01-01 |
publisher | IOP Publishing |
record_format | Article |
series | Materials Research Express |
spelling | doaj.art-83c80422c7924c59a39b4fc295f844f52023-08-09T15:26:30ZengIOP PublishingMaterials Research Express2053-15912020-01-017101610710.1088/2053-1591/ab66a4Manganese ferrite nanocubes as an MRI contrast agentM Ravichandran0https://orcid.org/0000-0002-2934-0717S Velumani1Centro de Física Aplicada y Tecnología Avanzada, Universidad Nacional Autónoma de México , Boulevard Juriquilla, Querétaro, Qro., México; Program on Nanoscience and Nanotechnology, CINVESTAV-IPN, Avenida IPN 6508, San Pedro Zacatenco, D F, MexicoProgram on Nanoscience and Nanotechnology, CINVESTAV-IPN, Avenida IPN 6508, San Pedro Zacatenco, D F, Mexico; Department of Electrical Engineering (SEES), CINVESTAV-IPN, Avenida IPN 6508, San Pedro Zacatenco, D F MexicoFacile synthesis of superparamagnetic, highly crystalline, manganese ferrite nanocubes (MnNCs) is reported. X-ray diffraction depicts single-phase face-centred cubic spinel and the electron microscopy represents the nearly monodispersed cube-like nanostructure with the size ranging from 18 to 20 nm. Vibrating sample magnetometer shows magnetization field-dependent curves at 300 K exhibiting the superparamagnetic behaviour of NCs with negligible remanence. Furthermore, the biocompatibility of NCs was proved by MTT assay. These unique characteristics make this NCs as a contrast agent ideally suited for T _2 -weighted MR imaging. This novel method of synthesizing NCs proves to be very attractive for various biomedical applications because of their outstanding stability and biocompatibility.https://doi.org/10.1088/2053-1591/ab66a4manganese ferritenanocubeMRIbiocompatiblesuperparamagnetic |
spellingShingle | M Ravichandran S Velumani Manganese ferrite nanocubes as an MRI contrast agent Materials Research Express manganese ferrite nanocube MRI biocompatible superparamagnetic |
title | Manganese ferrite nanocubes as an MRI contrast agent |
title_full | Manganese ferrite nanocubes as an MRI contrast agent |
title_fullStr | Manganese ferrite nanocubes as an MRI contrast agent |
title_full_unstemmed | Manganese ferrite nanocubes as an MRI contrast agent |
title_short | Manganese ferrite nanocubes as an MRI contrast agent |
title_sort | manganese ferrite nanocubes as an mri contrast agent |
topic | manganese ferrite nanocube MRI biocompatible superparamagnetic |
url | https://doi.org/10.1088/2053-1591/ab66a4 |
work_keys_str_mv | AT mravichandran manganeseferritenanocubesasanmricontrastagent AT svelumani manganeseferritenanocubesasanmricontrastagent |