Crosstalk between regulatory non-coding RNAs and oxidative stress in Parkinson’s disease
Parkinson’s disease is the second most common neurodegenerative disease after Alzheimer’s disease, which imposes an ever-increasing burden on society. Many studies have indicated that oxidative stress may play an important role in Parkinson’s disease through multiple processes related to dysfunction...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2022.975248/full |
| _version_ | 1811322489423265792 |
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| author | Hantao Zhang Xiaoyan Liu Yi Liu Yi Liu Junlin Liu Xun Gong Gang Li Min Tang |
| author_facet | Hantao Zhang Xiaoyan Liu Yi Liu Yi Liu Junlin Liu Xun Gong Gang Li Min Tang |
| author_sort | Hantao Zhang |
| collection | DOAJ |
| description | Parkinson’s disease is the second most common neurodegenerative disease after Alzheimer’s disease, which imposes an ever-increasing burden on society. Many studies have indicated that oxidative stress may play an important role in Parkinson’s disease through multiple processes related to dysfunction or loss of neurons. Besides, several subtypes of non-coding RNAs are found to be involved in this neurodegenerative disorder. However, the interplay between oxidative stress and regulatory non-coding RNAs in Parkinson’s disease remains to be clarified. In this article, we comprehensively survey and overview the role of regulatory ncRNAs in combination with oxidative stress in Parkinson’s disease. The interaction between them is also summarized. We aim to provide readers with a relatively novel insight into the pathogenesis of Parkinson’s disease, which would contribute to the development of pre-clinical diagnosis and treatment. |
| first_indexed | 2024-04-13T13:37:07Z |
| format | Article |
| id | doaj.art-83d0170d75504ecaa19b1da6a7307d94 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-04-13T13:37:07Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-83d0170d75504ecaa19b1da6a7307d942022-12-22T02:44:46ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652022-08-011410.3389/fnagi.2022.975248975248Crosstalk between regulatory non-coding RNAs and oxidative stress in Parkinson’s diseaseHantao Zhang0Xiaoyan Liu1Yi Liu2Yi Liu3Junlin Liu4Xun Gong5Gang Li6Min Tang7School of Life Sciences, Jiangsu University, Zhenjiang, ChinaSchool of Life Sciences, Jiangsu University, Zhenjiang, ChinaSchool of Life Sciences, Jiangsu University, Zhenjiang, ChinaInstitute of Animal Husbandry, Jiangsu Academy of Agricultural Sciences, Nanjing, ChinaSchool of Life Sciences, Jiangsu University, Zhenjiang, ChinaDepartment of Rheumatology & Immunology, Affiliated Hospital of Jiangsu University, Zhenjiang, ChinaDepartment of Vascular Surgery, The Second Affiliated Hospital of Shandong First Medical University, Taian, ChinaSchool of Life Sciences, Jiangsu University, Zhenjiang, ChinaParkinson’s disease is the second most common neurodegenerative disease after Alzheimer’s disease, which imposes an ever-increasing burden on society. Many studies have indicated that oxidative stress may play an important role in Parkinson’s disease through multiple processes related to dysfunction or loss of neurons. Besides, several subtypes of non-coding RNAs are found to be involved in this neurodegenerative disorder. However, the interplay between oxidative stress and regulatory non-coding RNAs in Parkinson’s disease remains to be clarified. In this article, we comprehensively survey and overview the role of regulatory ncRNAs in combination with oxidative stress in Parkinson’s disease. The interaction between them is also summarized. We aim to provide readers with a relatively novel insight into the pathogenesis of Parkinson’s disease, which would contribute to the development of pre-clinical diagnosis and treatment.https://www.frontiersin.org/articles/10.3389/fnagi.2022.975248/fullParkinson’s diseasemicroRNAslong non-coding RNAscircular RNAsoxidative stress |
| spellingShingle | Hantao Zhang Xiaoyan Liu Yi Liu Yi Liu Junlin Liu Xun Gong Gang Li Min Tang Crosstalk between regulatory non-coding RNAs and oxidative stress in Parkinson’s disease Frontiers in Aging Neuroscience Parkinson’s disease microRNAs long non-coding RNAs circular RNAs oxidative stress |
| title | Crosstalk between regulatory non-coding RNAs and oxidative stress in Parkinson’s disease |
| title_full | Crosstalk between regulatory non-coding RNAs and oxidative stress in Parkinson’s disease |
| title_fullStr | Crosstalk between regulatory non-coding RNAs and oxidative stress in Parkinson’s disease |
| title_full_unstemmed | Crosstalk between regulatory non-coding RNAs and oxidative stress in Parkinson’s disease |
| title_short | Crosstalk between regulatory non-coding RNAs and oxidative stress in Parkinson’s disease |
| title_sort | crosstalk between regulatory non coding rnas and oxidative stress in parkinson s disease |
| topic | Parkinson’s disease microRNAs long non-coding RNAs circular RNAs oxidative stress |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2022.975248/full |
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