An alternative therapy for idiopathic pulmonary fibrosis by doxycycline through matrix metalloproteinase inhibition

An alternative therapy for idiopathic pulmonary fibrosis by doxycycline through matrix metalloproteinase inhibition

Background: Idiopatiic pulmonary fibrosis (IPF) is a disease of dysregulated fibrogenesis with abnormal matrix metalloproteinase (MMPs) activity, angiogenesis, and profibrotic milieu wherein MMPs inhibition appears to be target-based therapy. We evaluated the role of doxycycline as a nonspecific inh...

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Bibliographic Details
Main Authors: Amartya Mishra, Parthasarathi Bhattacharya, Sumit Paul, Rantu Paul, Snehasikta Swarnakar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Lung India
Subjects:
Broncho alveolar lavage fluid
doxycycline
idiopathic pulmonary fibrosis
matrix metalloproteinase
vascular endothelial growth factor
Online Access:http://www.lungindia.com/article.asp?issn=0970-2113;year=2011;volume=28;issue=3;spage=174;epage=179;aulast=Mishra

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