Differentiation syndrome in acute promyelocytic leukemia: pathogenesis and risk factors Síndrome da diferenciação na leucemia promielocítica aguda: patogênese e fatores de risco

Differentiation syndrome in acute promyelocytic leukemia: pathogenesis and risk factors Síndrome da diferenciação na leucemia promielocítica aguda: patogênese e fatores de risco

Differentiation syndrome is a treatment complication which can occur in acute promyelocytic leukemia (APL) patients treated with all-trans retinoic acid (ATRA) or arsenic trioxide (ATO), which is characterized by enhanced leukocyte transmigration. Several cellular and molecular mechanisms participat...

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Bibliographic Details
Main Authors:	Eduardo M. Rego, Bárbara A. A. Santana-Lemos, Mirela B. Tamarozzi
Format:	Article
Language:	English
Published:	Elsevier 2008-06-01
Series:	Revista Brasileira de Hematologia e Hemoterapia
Subjects:	Leucemia promielocítica aguda moléculas de adesão retinóides trióxido de arsênico Acute promyelocytic leukemia adhesion molecules retinoids arsenic trioxide
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000800009

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