OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation
Abstract Background SD-OCT is becoming commonplace in everyday practice. Vitreomacular adhesions (VMAs) are being more routinely diagnosed. Predictive studies to the natural course of VMA are thus clinically significant. Spectral domain-optical coherence tomography (SD-OCT) was presently utilized to...
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| Format: | Article |
| Language: | English |
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BMC
2020-04-01
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| Series: | BMC Ophthalmology |
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| Online Access: | http://link.springer.com/article/10.1186/s12886-020-01416-x |
| _version_ | 1819019787535122432 |
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| author | Ding-Ying Liao Jorn-Hon Liu Yu-Ping Zheng Huei-Wen Shiu Jian-Ming Wang Hsiao-Ming Chao |
| author_facet | Ding-Ying Liao Jorn-Hon Liu Yu-Ping Zheng Huei-Wen Shiu Jian-Ming Wang Hsiao-Ming Chao |
| author_sort | Ding-Ying Liao |
| collection | DOAJ |
| description | Abstract Background SD-OCT is becoming commonplace in everyday practice. Vitreomacular adhesions (VMAs) are being more routinely diagnosed. Predictive studies to the natural course of VMA are thus clinically significant. Spectral domain-optical coherence tomography (SD-OCT) was presently utilized to analyze the incidence of floaters, the complete vitreomacular separation or VMA, the VMA complication, the vitreomacular angle (VMAng), and the complication mechanism. Methods Monthly SD-OCT was performed on patients with/without symptomatic floaters. OCT allowed VMA and vitreomacular separation to be compared. The incidence was assessed applying one-tailed Fisher’s exact tests. The VMAngs between the inner retina and posterior hyaloid were measured, and the complication mechanism was studied using OCT image. For macular hole (MH), pre- and/or post-operative best corrected visual acuities (BCVAs; LogMAR), refractions and photoreceptor conditions were also evaluated. Results Totally, 124 eyes were included; there were 116 eyes with VMA and 8 eyes with vitreomacular separation. Considering the percentages over 124 eyes, floaters were present in 14.5% of enrolled eyes (=18/124), consisting of 12.9% of eyes with VMA (16/124) and 1.6% of eyes with vitreomacular separation (2/124). Moreover, there were twelve eyes (9.7%) with VMA-associated vision-threatening complications, including MH (n = 8; 6.5%), retinal detachment (RD; n = 2; 1.6%), vitreomacular traction (VMT; n = 1; 0.8%) and macular pucker (MP; n = 1; 0.8%). Eyes with initial VMA had a significantly greater possibility of complications than eyes with initial vitreomacular separation (p = 0.03). Among these eyes with MH (n = 8), the pre-operative BCVA (LogMAR) was 1.1 ± 0.5, which was insignificantly (p = 0.35) improved to 0.8 ± 0.7 post-operatively. The VMAng of VMA eyes with MHs was 24.2 ± 24.9° (n = 8). The critical VMAng was 13.3°. Conclusions A minority of eyes with VMA or vitreomacular separation had floaters. Moreover, the use of SD-OCT could identify vision-threatening sequelae, namely MH, RD, MP and VMT, and this was significantly more frequent in eyes with VMA than in eyes with complete vitreomacular separation. Therefore, SD-OCT might be a useful way of identifying either identity, and evaluating VMA-associated complications. Whether VMA eyes with MH (n = 8) that have a VMAng greater than critical VMAng have a greater likelihood of tangential traction and subsequent MH needs further investigation. |
| first_indexed | 2024-12-21T03:40:52Z |
| format | Article |
| id | doaj.art-83d7e07926734293bf04ac6278bdba9b |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-21T03:40:52Z |
| publishDate | 2020-04-01 |
| publisher | BMC |
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| series | BMC Ophthalmology |
| spelling | doaj.art-83d7e07926734293bf04ac6278bdba9b2022-12-21T19:17:13ZengBMCBMC Ophthalmology1471-24152020-04-0120111010.1186/s12886-020-01416-xOCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separationDing-Ying Liao0Jorn-Hon Liu1Yu-Ping Zheng2Huei-Wen Shiu3Jian-Ming Wang4Hsiao-Ming Chao5Department of Ophthalmology, Second Affiliated Hospital, Xi’an Jiaotong UniversityDepartment of Ophthalmology, Cheng Hsin General HospitalDepartment of Ophthalmology, Second Affiliated Hospital, Xi’an Jiaotong UniversityDepartment of Ophthalmology, Cheng Hsin General HospitalDepartment of Ophthalmology, Second Affiliated Hospital, Xi’an Jiaotong UniversityDepartment of Ophthalmology, Cheng Hsin General HospitalAbstract Background SD-OCT is becoming commonplace in everyday practice. Vitreomacular adhesions (VMAs) are being more routinely diagnosed. Predictive studies to the natural course of VMA are thus clinically significant. Spectral domain-optical coherence tomography (SD-OCT) was presently utilized to analyze the incidence of floaters, the complete vitreomacular separation or VMA, the VMA complication, the vitreomacular angle (VMAng), and the complication mechanism. Methods Monthly SD-OCT was performed on patients with/without symptomatic floaters. OCT allowed VMA and vitreomacular separation to be compared. The incidence was assessed applying one-tailed Fisher’s exact tests. The VMAngs between the inner retina and posterior hyaloid were measured, and the complication mechanism was studied using OCT image. For macular hole (MH), pre- and/or post-operative best corrected visual acuities (BCVAs; LogMAR), refractions and photoreceptor conditions were also evaluated. Results Totally, 124 eyes were included; there were 116 eyes with VMA and 8 eyes with vitreomacular separation. Considering the percentages over 124 eyes, floaters were present in 14.5% of enrolled eyes (=18/124), consisting of 12.9% of eyes with VMA (16/124) and 1.6% of eyes with vitreomacular separation (2/124). Moreover, there were twelve eyes (9.7%) with VMA-associated vision-threatening complications, including MH (n = 8; 6.5%), retinal detachment (RD; n = 2; 1.6%), vitreomacular traction (VMT; n = 1; 0.8%) and macular pucker (MP; n = 1; 0.8%). Eyes with initial VMA had a significantly greater possibility of complications than eyes with initial vitreomacular separation (p = 0.03). Among these eyes with MH (n = 8), the pre-operative BCVA (LogMAR) was 1.1 ± 0.5, which was insignificantly (p = 0.35) improved to 0.8 ± 0.7 post-operatively. The VMAng of VMA eyes with MHs was 24.2 ± 24.9° (n = 8). The critical VMAng was 13.3°. Conclusions A minority of eyes with VMA or vitreomacular separation had floaters. Moreover, the use of SD-OCT could identify vision-threatening sequelae, namely MH, RD, MP and VMT, and this was significantly more frequent in eyes with VMA than in eyes with complete vitreomacular separation. Therefore, SD-OCT might be a useful way of identifying either identity, and evaluating VMA-associated complications. Whether VMA eyes with MH (n = 8) that have a VMAng greater than critical VMAng have a greater likelihood of tangential traction and subsequent MH needs further investigation.http://link.springer.com/article/10.1186/s12886-020-01416-xVitreomacular adhesionVitreomacular separationIncidenceMacular holeVitreomacular angle |
| spellingShingle | Ding-Ying Liao Jorn-Hon Liu Yu-Ping Zheng Huei-Wen Shiu Jian-Ming Wang Hsiao-Ming Chao OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation BMC Ophthalmology Vitreomacular adhesion Vitreomacular separation Incidence Macular hole Vitreomacular angle |
| title | OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation |
| title_full | OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation |
| title_fullStr | OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation |
| title_full_unstemmed | OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation |
| title_short | OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation |
| title_sort | oct proves that vitreomacular adhesion is significantly more likely to develop vision threatening retinal complications than vitreomacular separation |
| topic | Vitreomacular adhesion Vitreomacular separation Incidence Macular hole Vitreomacular angle |
| url | http://link.springer.com/article/10.1186/s12886-020-01416-x |
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