Radiation therapy before radical cystectomy combined with immunotherapy in locally advanced bladder cancer – study protocol of a prospective, single arm, multicenter phase II trial (RACE IT)

Radiation therapy before radical cystectomy combined with immunotherapy in locally advanced bladder cancer – study protocol of a prospective, single arm, multicenter phase II trial (RACE IT)

Abstract Background Patients with locally advanced bladder cancer (cT3/4 cN0/N+ cM0) have a poor prognosis despite radical surgical therapy and perioperative chemotherapy. Preliminary data suggest that the combination of radiation and immunotherapy does not lead to excess toxicity and may have syner...

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Bibliographic Details
Main Authors: Sebastian C. Schmid, Florestan J. Koll, Claus Rödel, Philipp Maisch, Andreas Sauter, Franziska Beckert, Anna Seitz, Hubert Kübler, Michael Flentje, Felix Chun, Stephanie E. Combs, Kilian Schiller, Jürgen E. Gschwend, Margitta Retz
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Cancer
Subjects:
Bladder cancer
Urothelial cancer
Transitional cell carcinoma
Locally advanced
Immunotherapy
Radiotherapy
Online Access:https://doi.org/10.1186/s12885-019-6503-6

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