The Impact of PEGylation on Cellular Uptake and In Vivo Biodistribution of Gold Nanoparticle MRI Contrast Agents

The Impact of PEGylation on Cellular Uptake and In Vivo Biodistribution of Gold Nanoparticle MRI Contrast Agents

Gold nanoparticles (GNPs) have immense potential in biomedicine, but understanding their interactions with serum proteins is crucial as it could change their biological profile due to the formation of a protein corona, which could then affect their ultimate biodistribution in the body. Grafting GNPs...

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Bibliographic Details
Main Authors: Nagwa El-Baz, Betty M. Nunn, Paula J. Bates, Martin G. O’Toole
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Bioengineering
Subjects:
gold nanoparticle
AS1411
gadolinium chelate
polyethylene glycol
cancer-targeted
opsonization
Online Access:https://www.mdpi.com/2306-5354/9/12/766

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