A Prospective Study of the Surgical Outcome of Simple Uvulopalatopharyngoplasty (UPPP), UPPP Combined With Genioglossus Advancement or Tongue Base Advancement for Obstructive Sleep Apnea Hypopnea Syndrome Patients With Multilevel Obstruction

ObjectivesTo investigate the surgical outcomes of different uvulopalatopharyngoplasty (UPPP).Methods All subjects underwent overnight polysomnography and were evaluated using the Epworth sleepiness scale (ESS), the Quebec sleep questionnaire and the snoring scale at the baseline and 3 and 12 months...

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Main Authors: Shicai Chen, Song Shi, Yanghui Xia, Minhui Zhu, Caiyun Zhang, Siwen Xia, Hongliang Zheng
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2015-06-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Online Access:http://www.e-ceo.org/upload/pdf/ceo-8-136.pdf
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author Shicai Chen
Song Shi
Yanghui Xia
Minhui Zhu
Caiyun Zhang
Siwen Xia
Hongliang Zheng
author_facet Shicai Chen
Song Shi
Yanghui Xia
Minhui Zhu
Caiyun Zhang
Siwen Xia
Hongliang Zheng
author_sort Shicai Chen
collection DOAJ
description ObjectivesTo investigate the surgical outcomes of different uvulopalatopharyngoplasty (UPPP).Methods All subjects underwent overnight polysomnography and were evaluated using the Epworth sleepiness scale (ESS), the Quebec sleep questionnaire and the snoring scale at the baseline and 3 and 12 months following operation. The primary endpoint was the overall effective rate representing the sum of the surgical success rate and effective rate.ResultsThe overall effective rate at 12 months post surgery was 55.6% for simple UPPP, 95.8% for UPPP+GA, and 92.3% for UPPP+TBA. The surgical success rate at 3 and 12 months postoperation for UPPP+GA or UPPP+TBA was significantly higher than simple UPPP (P<0.05). Marked improvement was observed in all patients in the snoring scale score and the ESS score 3 and 12 months following surgery compared to the baseline (P<0.05 in all).ConclusionUPPP, UPPP+GA, and UPPP+TBA are all effective in improving the surgical outcome of obstructive sleep apnea hypopnea syndrome (OSAHS) patients with multilevel obstruction. UPPP+TBA appears to be the most effective in treating OSAHS patients.
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spelling doaj.art-83db6dadaa0645229b816bbcdb35a9a02022-12-22T03:36:09ZengKorean Society of Otorhinolaryngology-Head and Neck SurgeryClinical and Experimental Otorhinolaryngology1976-87102005-07202015-06-018213614110.3342/ceo.2015.8.2.136354A Prospective Study of the Surgical Outcome of Simple Uvulopalatopharyngoplasty (UPPP), UPPP Combined With Genioglossus Advancement or Tongue Base Advancement for Obstructive Sleep Apnea Hypopnea Syndrome Patients With Multilevel ObstructionShicai Chen0Song Shi1Yanghui Xia2Minhui Zhu3Caiyun Zhang4Siwen Xia5Hongliang Zheng6Department of Otorhinolaryngology-Head and Neck Surgery, Changhai Hospital, Second Military Medical University of PLA, Shanghai, China.Department of Otorhinolaryngology-Head and Neck Surgery, Changhai Hospital, Second Military Medical University of PLA, Shanghai, China.Department of Otorhinolaryngology-Head and Neck Surgery, Changhai Hospital, Second Military Medical University of PLA, Shanghai, China.Department of Otorhinolaryngology-Head and Neck Surgery, Changhai Hospital, Second Military Medical University of PLA, Shanghai, China.Department of Otorhinolaryngology-Head and Neck Surgery, Changhai Hospital, Second Military Medical University of PLA, Shanghai, China.Department of Otorhinolaryngology-Head and Neck Surgery, Changhai Hospital, Second Military Medical University of PLA, Shanghai, China.Department of Otorhinolaryngology-Head and Neck Surgery, Changhai Hospital, Second Military Medical University of PLA, Shanghai, China.ObjectivesTo investigate the surgical outcomes of different uvulopalatopharyngoplasty (UPPP).Methods All subjects underwent overnight polysomnography and were evaluated using the Epworth sleepiness scale (ESS), the Quebec sleep questionnaire and the snoring scale at the baseline and 3 and 12 months following operation. The primary endpoint was the overall effective rate representing the sum of the surgical success rate and effective rate.ResultsThe overall effective rate at 12 months post surgery was 55.6% for simple UPPP, 95.8% for UPPP+GA, and 92.3% for UPPP+TBA. The surgical success rate at 3 and 12 months postoperation for UPPP+GA or UPPP+TBA was significantly higher than simple UPPP (P<0.05). Marked improvement was observed in all patients in the snoring scale score and the ESS score 3 and 12 months following surgery compared to the baseline (P<0.05 in all).ConclusionUPPP, UPPP+GA, and UPPP+TBA are all effective in improving the surgical outcome of obstructive sleep apnea hypopnea syndrome (OSAHS) patients with multilevel obstruction. UPPP+TBA appears to be the most effective in treating OSAHS patients.http://www.e-ceo.org/upload/pdf/ceo-8-136.pdfSleep Apnea SyndromesUvulopalatopharyngoplastyGenioglossus AdvancementTongue Base AdvancementRepose SystemEpworth Sleepiness Scale
spellingShingle Shicai Chen
Song Shi
Yanghui Xia
Minhui Zhu
Caiyun Zhang
Siwen Xia
Hongliang Zheng
A Prospective Study of the Surgical Outcome of Simple Uvulopalatopharyngoplasty (UPPP), UPPP Combined With Genioglossus Advancement or Tongue Base Advancement for Obstructive Sleep Apnea Hypopnea Syndrome Patients With Multilevel Obstruction
Clinical and Experimental Otorhinolaryngology
Sleep Apnea Syndromes
Uvulopalatopharyngoplasty
Genioglossus Advancement
Tongue Base Advancement
Repose System
Epworth Sleepiness Scale
title A Prospective Study of the Surgical Outcome of Simple Uvulopalatopharyngoplasty (UPPP), UPPP Combined With Genioglossus Advancement or Tongue Base Advancement for Obstructive Sleep Apnea Hypopnea Syndrome Patients With Multilevel Obstruction
title_full A Prospective Study of the Surgical Outcome of Simple Uvulopalatopharyngoplasty (UPPP), UPPP Combined With Genioglossus Advancement or Tongue Base Advancement for Obstructive Sleep Apnea Hypopnea Syndrome Patients With Multilevel Obstruction
title_fullStr A Prospective Study of the Surgical Outcome of Simple Uvulopalatopharyngoplasty (UPPP), UPPP Combined With Genioglossus Advancement or Tongue Base Advancement for Obstructive Sleep Apnea Hypopnea Syndrome Patients With Multilevel Obstruction
title_full_unstemmed A Prospective Study of the Surgical Outcome of Simple Uvulopalatopharyngoplasty (UPPP), UPPP Combined With Genioglossus Advancement or Tongue Base Advancement for Obstructive Sleep Apnea Hypopnea Syndrome Patients With Multilevel Obstruction
title_short A Prospective Study of the Surgical Outcome of Simple Uvulopalatopharyngoplasty (UPPP), UPPP Combined With Genioglossus Advancement or Tongue Base Advancement for Obstructive Sleep Apnea Hypopnea Syndrome Patients With Multilevel Obstruction
title_sort prospective study of the surgical outcome of simple uvulopalatopharyngoplasty uppp uppp combined with genioglossus advancement or tongue base advancement for obstructive sleep apnea hypopnea syndrome patients with multilevel obstruction
topic Sleep Apnea Syndromes
Uvulopalatopharyngoplasty
Genioglossus Advancement
Tongue Base Advancement
Repose System
Epworth Sleepiness Scale
url http://www.e-ceo.org/upload/pdf/ceo-8-136.pdf
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