Design, Synthesis, In Vitro, and In Silico Insights of 5-(Substituted benzylidene)-2-phenylthiazol-4(5<i>H</i>)-one Derivatives: A Novel Class of Anti-Melanogenic Compounds
(<i>Z</i>)-5-Benzylidene-2-phenylthiazol-4(5<i>H</i>)-one ((<i>Z</i>)-BPT) derivatives were designed by combining the structural characteristics of two tyrosinase inhibitors. The double-bond geometry of trisubstituted alkenes, (<i>Z</i>)-BPTs <b>...
Main Authors: | Dahye Yoon, Min Kyung Kang, Hee Jin Jung, Sultan Ullah, Jieun Lee, Yeongmu Jeong, Sang Gyun Noh, Dongwan Kang, Yujin Park, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-04-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/28/8/3293 |
Similar Items
-
Identification of (Z)-2-benzylidene-dihydroimidazothiazolone derivatives as tyrosinase inhibitors: Anti-melanogenic effects and in silico studies
by: Heejeong Choi, et al.
Published: (2022-01-01) -
Design and Synthesis of (<i>Z</i>)-2-(Benzylamino)-5-benzylidenethiazol-4(5<i>H</i>)-one Derivatives as Tyrosinase Inhibitors and Their Anti-Melanogenic and Antioxidant Effects
by: Jieun Lee, et al.
Published: (2023-01-01) -
Identification of a Novel Class of Anti-Melanogenic Compounds, (<i>Z</i>)-5-(Substituted benzylidene)-3-phenyl-2-thioxothiazolidin-4-one Derivatives, and Their Reactive Oxygen Species Scavenging Activities
by: Yeongmu Jeong, et al.
Published: (2022-05-01) -
Design and Synthesis of (<i>Z</i>)-5-(Substituted benzylidene)-3-cyclohexyl-2-thioxothiazolidin-4-one Analogues as Anti-Tyrosinase and Antioxidant Compounds: In Vitro and In Silico Insights
by: Jeongin Ko, et al.
Published: (2022-09-01) -
Anti-Melanogenic Effects of Fractioned <i>Cynanchum atratum</i> by Regulation of cAMP/MITF Pathway in a UVB-Stimulated Mice Model
by: Jing-Hua Wang, et al.
Published: (2023-05-01)