Posterior urethral valves: 10 years audit of epidemiologic, diagnostic and therapeutic aspects in Yaoundé gynaeco-obstetric and paediatric hospital

Abstract Background The incidence of posterior urethral valve (PUV) is estimated at 1:5000–1:8000 males. It is the most common paediatric urologic urgency and the most common cause of male obstructive uropathy and chronic renal failure in children. The study aimed to describe the experience of Yaoun...

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Main Authors: Faustin Felicien Mouafo Tambo, Paul Nkemtendong Tolefac, Marcelin Ngowe Ngowe, Jacqueline Ze Minkande, Landry Mbouche, Georgette Guemkam, Neville Alemnju Telelen, Fru Fobuzshi Angwafo, Aurelien Maurice Sosso
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Urology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12894-018-0364-1
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author Faustin Felicien Mouafo Tambo
Paul Nkemtendong Tolefac
Marcelin Ngowe Ngowe
Jacqueline Ze Minkande
Landry Mbouche
Georgette Guemkam
Neville Alemnju Telelen
Fru Fobuzshi Angwafo
Aurelien Maurice Sosso
author_facet Faustin Felicien Mouafo Tambo
Paul Nkemtendong Tolefac
Marcelin Ngowe Ngowe
Jacqueline Ze Minkande
Landry Mbouche
Georgette Guemkam
Neville Alemnju Telelen
Fru Fobuzshi Angwafo
Aurelien Maurice Sosso
author_sort Faustin Felicien Mouafo Tambo
collection DOAJ
description Abstract Background The incidence of posterior urethral valve (PUV) is estimated at 1:5000–1:8000 males. It is the most common paediatric urologic urgency and the most common cause of male obstructive uropathy and chronic renal failure in children. The study aimed to describe the experience of Yaoundé gynaeco-obstetrics and paediatric hospital in the management of PUV. Methods Retrospectively, medical records were retrieved over a ten year period and all data recorded and analyzed for study objectives. Patients were called and evaluated for outcomes regarding morbidity and mortality. Results A total of 18 patients all males were managed over the ten year period, given prevalence of 13 cases/100,000 admissions and an admission rate of 2 per annum. The median age at presentation was 22 months and 13 (72.2%) participants presented late. Voiding urethrocystogram was done in all the participants where it showed dilated and elongated posterior urethral valves in 16 (88.9%) of the cases. Endoscopic valve ablation resulted in the relief of obstruction in all but 3 (16.7%) participants that had residual valves and 2 (11.2%) participants that had urethral stenosis. Type I valves were most common in 14 (78.0%) participants. The mean duration of follow up was 34.56 ± 21.47 months. Complications at final follow up were: 10 (55.6%) chronic renal failure, 2 (11.2%) end-stage renal failure. The case fatality rate was 5.6%. Conclusion Many patients present late in our setting with already established complications. There is the need to counsel parents/guardians on the importance of long-term follow up after relief of obstruction.
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spelling doaj.art-83e2cbfd181a4fc1b36e8acf6d69440d2022-12-21T22:24:55ZengBMCBMC Urology1471-24902018-05-011811710.1186/s12894-018-0364-1Posterior urethral valves: 10 years audit of epidemiologic, diagnostic and therapeutic aspects in Yaoundé gynaeco-obstetric and paediatric hospitalFaustin Felicien Mouafo Tambo0Paul Nkemtendong Tolefac1Marcelin Ngowe Ngowe2Jacqueline Ze Minkande3Landry Mbouche4Georgette Guemkam5Neville Alemnju Telelen6Fru Fobuzshi Angwafo7Aurelien Maurice Sosso8Departmennt of Surgery and Subspecialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1Specialized Internship Program, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1Department of Surgery, Faculty of Health Sciences, University of BueaDepartment of Anaesthesia and Intensive Care, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1Paediatric Surgery Unit, Yaoundé Gynaeco-Obstetric and Paediatric HospitalPaediatric Nephrology Unit, Mother and Child Centre, Chantal Biya FoundationDepartment of Surgery, Faculty of Health Sciences, University of BueaDepartmennt of Surgery and Subspecialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1Departmennt of Surgery and Subspecialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1Abstract Background The incidence of posterior urethral valve (PUV) is estimated at 1:5000–1:8000 males. It is the most common paediatric urologic urgency and the most common cause of male obstructive uropathy and chronic renal failure in children. The study aimed to describe the experience of Yaoundé gynaeco-obstetrics and paediatric hospital in the management of PUV. Methods Retrospectively, medical records were retrieved over a ten year period and all data recorded and analyzed for study objectives. Patients were called and evaluated for outcomes regarding morbidity and mortality. Results A total of 18 patients all males were managed over the ten year period, given prevalence of 13 cases/100,000 admissions and an admission rate of 2 per annum. The median age at presentation was 22 months and 13 (72.2%) participants presented late. Voiding urethrocystogram was done in all the participants where it showed dilated and elongated posterior urethral valves in 16 (88.9%) of the cases. Endoscopic valve ablation resulted in the relief of obstruction in all but 3 (16.7%) participants that had residual valves and 2 (11.2%) participants that had urethral stenosis. Type I valves were most common in 14 (78.0%) participants. The mean duration of follow up was 34.56 ± 21.47 months. Complications at final follow up were: 10 (55.6%) chronic renal failure, 2 (11.2%) end-stage renal failure. The case fatality rate was 5.6%. Conclusion Many patients present late in our setting with already established complications. There is the need to counsel parents/guardians on the importance of long-term follow up after relief of obstruction.http://link.springer.com/article/10.1186/s12894-018-0364-1Posterior urethral valvesEpidemiologicDiagnosticYaoundéLate presentation
spellingShingle Faustin Felicien Mouafo Tambo
Paul Nkemtendong Tolefac
Marcelin Ngowe Ngowe
Jacqueline Ze Minkande
Landry Mbouche
Georgette Guemkam
Neville Alemnju Telelen
Fru Fobuzshi Angwafo
Aurelien Maurice Sosso
Posterior urethral valves: 10 years audit of epidemiologic, diagnostic and therapeutic aspects in Yaoundé gynaeco-obstetric and paediatric hospital
BMC Urology
Posterior urethral valves
Epidemiologic
Diagnostic
Yaoundé
Late presentation
title Posterior urethral valves: 10 years audit of epidemiologic, diagnostic and therapeutic aspects in Yaoundé gynaeco-obstetric and paediatric hospital
title_full Posterior urethral valves: 10 years audit of epidemiologic, diagnostic and therapeutic aspects in Yaoundé gynaeco-obstetric and paediatric hospital
title_fullStr Posterior urethral valves: 10 years audit of epidemiologic, diagnostic and therapeutic aspects in Yaoundé gynaeco-obstetric and paediatric hospital
title_full_unstemmed Posterior urethral valves: 10 years audit of epidemiologic, diagnostic and therapeutic aspects in Yaoundé gynaeco-obstetric and paediatric hospital
title_short Posterior urethral valves: 10 years audit of epidemiologic, diagnostic and therapeutic aspects in Yaoundé gynaeco-obstetric and paediatric hospital
title_sort posterior urethral valves 10 years audit of epidemiologic diagnostic and therapeutic aspects in yaounde gynaeco obstetric and paediatric hospital
topic Posterior urethral valves
Epidemiologic
Diagnostic
Yaoundé
Late presentation
url http://link.springer.com/article/10.1186/s12894-018-0364-1
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